Evidence map›Paper›PMID 34109322›Full record

ArticleJournal of affective disorders reports2021

A lifetime of challenges: real-life decision outcomes in early- and late-onset suicide attempters.

M Perry, M Buerke, A Szücs, T A Allen, W Bruine de Bruin, K Szanto, A Y Dombrovski

Abstract read
In one paragraph

Article in Journal of affective disorders reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Is Late-Onset Suicidal Behavior a Distinct Subtype?The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024
    Review
  8. Life-Satisfaction, Engagement, Mindfulness, Flourishing, and Social Support: Do they Predict Depression, Suicide Ideation, and History of Suicide Attempt in Late Life?The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2023
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M PerryDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
M BuerkeDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
A SzücsDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
T A AllenDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
W Bruine de BruinDepartment of Public Policy, University of Southern California, Los Angeles, CA, United States.
K SzantoDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
A Y DombrovskiDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.

Funding

PSYCHOBIOLOGY OF SUICIDAL BEHAVIOR IN BPDR01MH048463 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Alexandre Y. Dombrovski · 1992 to 2026
$13.9M
Short Term Variability in Affect and Rest Activity Rhythms in Long Term Chronic and Highly Variable Suicidal Ideation in Depressed Older AdultsR01MH085651 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HANGA CSILLA GALFALVY, Swathi Gujral · 2010 to 2026
$9.6M
Reward Learning in Late-Life Suicidal BehaviorR01MH100095 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Alexandre Y. Dombrovski · 2014 to 2026
$6.8M
Training for Transformative Discovery in PsychiatryT32MH016804 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SWEET, ROBERT A · 1985 to 2025
$6.2M
NIMH NIH HHS R01 MH048463NIMH NIH HHS R01 MH085651NIMH NIH HHS R01 MH100095NIMH NIH HHS T32 MH016804
6 · The paper itself

Abstract

backgroundPeople who have attempted suicide display suboptimal decision-making in the lab. Yet, it remains unclear whether these difficulties tie in with other detrimental outcomes in their lives besides suicidal behavior. We hypothesize that this is more likely the case for individuals who first attempted suicide earlier than later in life.

methodsA cross-sectional case-control study of 310 adults aged ≥ 50 years (mean: 63.9), compared early- and late-onset attempters (first attempt < 55 vs. ≥ 55 years of age) to suicide ideators, non-suicidal depressed controls and non-psychiatric healthy controls. Participants reported potentially avoidable negative decision outcomes across their lifetime, using the Decision Outcome Inventory (DOI). We employed multi-level modeling to examine group differences overall, and in three factor-analytically derived domains labeled

resultsPsychopathology predicted worse decision outcomes overall, and in the more serious Acting Out and Lack of Future Planning domains, but not in Hassles. Early-onset attempters experienced more negative outcomes than other groups overall, in Lack of Future Planning, and particularly in Acting Out. Late-onset attempters were similar to depressed controls and experienced fewer Acting out outcomes than ideators. LIMITATIONS: The cross-sectional design precluded prospective prediction of attempts. The assessment of negative outcomes may have lacked precision due to recall bias.

conclusionsWhereas early-onset suicidal behavior is likely the manifestation of long-lasting decision-making deficits in several serious aspects of life, late-onset cases appear to function similarly to non-suicidal depressed adults, suggesting that their attempt originates from a more isolated crisis.

Indexed as

decision-makingexternalizinglife outcomesold agesuicidal behaviorsuicidal ideation

Identifiers

PMID34109322
PMCPMC8186299

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.