Evidence map›Paper›PMID 34109092›Full record

Article3 Biotech2021

Correlation of Cry1Ac mRNA and protein abundance in transgenic

P K Smitha, Christopher Bathula, Anil M Kumar, K N Chandrashekara, Sujan K Dhar, Manjula Das

Abstract read
In one paragraph

Article in 3 Biotech, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

P K SmithaTumor Immunology Program, MSMF, Mazumdar Shaw Medical Centre, Narayana Health City, 8th floor, Bommasandra, Bangalore, 560 099 Karnataka India.
Christopher BathulaTumor Immunology Program, MSMF, Mazumdar Shaw Medical Centre, Narayana Health City, 8th floor, Bommasandra, Bangalore, 560 099 Karnataka India.
Anil M KumarIncite Lab, MSMF, Mazumdar Shaw Medical Centre, Beyond Antibody, Narayana Health City, 8th floor, Bommasandra, Bangalore, 560 099 Karnataka India.
K N ChandrashekaraDivision of Plant Physiology and Biotechnology, UPASI Tea Research Foundation, Tea Research Institute, Nirar Dam, Valparai, Coimbatore, 642 127 Tamil Nadu India.
Sujan K DharIncite Lab, MSMF, Mazumdar Shaw Medical Centre, Beyond Antibody, Narayana Health City, 8th floor, Bommasandra, Bangalore, 560 099 Karnataka India.
Manjula DasTumor Immunology Program, MSMF, Mazumdar Shaw Medical Centre, Narayana Health City, 8th floor, Bommasandra, Bangalore, 560 099 Karnataka India.ORCID 0000-0001-6202-3919

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcription and translation in eukaryotes are distinct processes of the molecular cascade leading to protein production from genetic material. However, establishing correlation between mRNA expression and protein abundance, the end results of the two processes of central dogma, remains a challenge. For transgenic plants, such correlation between mRNA and protein expression serves as a guide to design the transgene, in particular the choices of promoter and codon usage to ensure stable expression of the target protein in relevant tissues under various stress conditions. To elucidate level of mRNA-protein correlation in a commercial transgenic cotton plant SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13205-021-02828-2.

Indexed as

CorrelationEnzyme-linked immunosorbent assay (ELISA)Real-time PCR (qPCR)Transgenic cotton

Identifiers

PMID34109092
PMCPMC8141090

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.