ArticleFrontiers in immunology2021
Functional Polymorphism in the
Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- The association between the monocyte Chemoattractant protein-1-2518A/G polymorphism and the risk of tuberculosis in the Chinese population: A meta-analysis and systematic review.Clinics (Sao Paulo, Brazil) · 2025Pooled it
- Article
- NRF2-mediated inhibition of alveolar macrophage MHC II expression during Mycobacterium tuberculosis infection.Cell reports · 2026Article
- BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility.Nature microbiology · 2024Article
- Identification of immune infiltration and cuproptosis-related molecular clusters in tuberculosis.Frontiers in immunology · 2023Article
- Roles of the m6A methyltransferases METTL3, METTL14, and WTAP in pulmonary tuberculosis.Frontiers in immunology · 2022Article
- Association of Three SNPs Loci of Kelch-Like-ECH-Associated Protein 1 (Human) with Tuberculosis in Chinese Han Population.International journal of general medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Nuclear transcription factor erythroid 2 p45-related factor 2 (Nrf2), encoded by Methods: 1950 unrelated Chinese Han participants were included in our two independent study groups. Five tag polymorphisms were selected and genotyped. The functional effects of the rs13005431 polymorphism were confirmed by dual-luciferase reporter assays and mRNA level comparisons. Results: Rs13005431_C and rs2364723_G were associated with increased TB susceptibility ( Conclusions: Our study suggests that allele C of rs13005431 might increase the susceptibility to TB by down-regulating the transcriptional activity of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.