ArticleFrontiers in psychology2021
Lockdown Effects on Healthy Cognitive Aging During the COVID-19 Pandemic: A Longitudinal Study.
Article in Frontiers in psychology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The impact of social isolation from COVID-19-related public health measures on cognitive function and mental health among older adults: A systematic review and meta-analysis.Ageing research reviews · 2023Pooled it
- The global evolution of mental health problems during the COVID-19 pandemic: A systematic review and meta-analysis of longitudinal studies.Journal of affective disorders · 2022Pooled it
- Trial
- A Prefrontal Neuromodulation Route for Post-Traumatic Olfactory Dysfunction: A Perspective Supported by Recovery During Left-DLPFC rTMS.Brain sciences · 2026Article
- Exploring cortical excitability modulation to promote cognitive resilience in aging: an rTMS study protocol.Frontiers in human neuroscience · 2026Article
- Article
- Longitudinal assessment of pragmatic and cognitive decay in healthy aging, and interplay with subjective cognitive decline and cognitive reserve.Scientific reports · 2025Article
- Physical Activity and Neurocognitive Symptoms in Older Adults During COVID-19 Pandemic.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025Article
- Editorial: Reviews in neuropsychology.Frontiers in psychology · 2024Article
- Addressing Long COVID Sequelae and Neurocovid: Neuropsychological Scenarios and Neuroimaging Findings.Advances in experimental medicine and biology · 2024Review
- A unique neuropsychophysiological approach to objectify emotion (dys)regulation in healthy older adults during the COVID-19 pandemic.Scientific reports · 2023Article
- Frailty after COVID-19: The wave after?Aging medicine (Milton (N.S.W)) · 2023Review
- Two-year follow-up of patients with post-COVID-19 condition in Sweden: a prospective cohort study.The Lancet regional health. Europe · 2023Article
- How consumer behaviours changed in response to COVID-19 lockdown stringency measures: A case study of Walmart.Applied geography (Sevenoaks, England) · 2023Article
- The neuropsychology of healthy aging: the positive context of the University of the Third Age during the COVID-19 pandemic.Scientific reports · 2023Article
- Impact of COVID-19 infection on cognition and its association with neurological symptoms.Brain and behavior · 2023Article
- Older Adults' Frequency of Going Outside during the COVID-19 Pandemic: Associations with Physical Distancing, Health Status, and Fall Risk Factors.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2023Article
- Editorial: Insights in neuropsychology 2021.Frontiers in psychology · 2023Article
- Lockdown Fatigue in Pediatric Respiratory Patients: Lessons from the First COVID-19 Year.Children (Basel, Switzerland) · 2022Article
- Effects of the COVID-19 Pandemic on Physical Function of Community-Dwelling People with Disabilities in Japan.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The COVID-19 pandemic is a health issue leading older adults to an increased vulnerability to unfavorable outcomes. Indeed, the presence of physical frailty has recently led to higher mortality due to SARS-CoV-2 infection. However, no longitudinal studies have investigated the role of neuropsychogeriatric factors associated with lockdown fatigue in healthy cognitive aging. Eighty-one healthy older adults were evaluated for their neuropsychological characteristics, including physical frailty, before the pandemic (T0). Subsequently, 50 of them agreed to be interviewed and neuropsychologically re-assessed during the lockdown (T1) and immediately after it (T2). Moreover, during another home confinement, they performed a psychological screening (T3) to evaluate possible mood changes and fatigue. According to Fried's frailty criteria, at T0, 63% of the sample was robust, 34.5% pre-frail, and only 2.5% frail. Significantly, these subjects presented a decrease in handgrip strength and walking speed (29.6 and 6.1%, respectively). Results from Principal Component Analyses and multiple regression models highlighted the contribution of "cognitive" and "psychological" factors (i.e., attentive-executive performance and mood deflections) in explaining handgrip strength and gait speed. At T3, lockdown fatigue was explained by higher scores on the Beck Depression Inventory and lower scores on the Trail Making Test part A. Results from a moderated-mediation model showed that the effect of psychomotor speed on lockdown fatigue was mediated by depression, with a moderating effect of gait speed. Our findings highlight the complex interrelationship between cognitive, psychological, and physical factors in the emergence of pandemic fatigue in a carefully selected older population.
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