Evidence map›Paper›PMID 34108880›Full record

ArticleFrontiers in pharmacology2021

Pharmacokinetics-Based Chronoefficacy of

Jingpan Lin, Lu Gao, Yanke Lin, Shuai Wang, Zemin Yang, Shujing Ren, Min Chen, Baojian Wu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Study on the Potential Mechanism ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jingpan LinCollege of Pharmacy, Jinan University, Guangzhou, China.
Lu GaoCollege of Pharmacy, Jinan University, Guangzhou, China.
Yanke LinCollege of Pharmacy, Jinan University, Guangzhou, China.
Shuai WangCollege of Pharmacy, Jinan University, Guangzhou, China.
Zemin YangCollege of Pharmacy, Jinan University, Guangzhou, China.
Shujing RenCollege of Pharmacy, Jinan University, Guangzhou, China.
Min ChenCollege of Pharmacy, Jinan University, Guangzhou, China.
Baojian WuInstitute of Molecular Rhythm and Metabolism, Guangzhou University of Chinese Medicine, Guangzhou, China.
Guangzhou University of Chinese Medicine · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis is a systemic autoimmune disease characterized by synovial inflammation and bone destruction. Identifying drugs with time-varying efficacy and toxicity, and elucidating the mechanisms would help to improve treatment efficacy and reduce adverse effects. Here, we aimed to determine the chronoefficacy of

Indexed as

chronoefficacydosing timepharmacokineticsrheumatoid arthritissemen strychnitripterygium glycoside tablet

Identifiers

PMID34108880
PMCPMC8181759
OpenAlexW3164184195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.