Evidence map›Paper›PMID 34108879›Full record

ArticleFrontiers in pharmacology2021

Astragaloside IV Attenuates the Myocardial Injury Caused by Adriamycin by Inhibiting Autophagy.

Li-Fei Luo, Lu-Yun Qin, Jian-Xin Wang, Peng Guan, Na Wang, En-Sheng Ji

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  6. Beyond Traditional Use: The Scientific Evidence for the Role ofPharmaceuticals (Basel, Switzerland) · 2025
    Review
  7. Research Progress on Chemical Components ofMolecules (Basel, Switzerland) · 2025
    Review
  8. Review
  9. Article
  10. Astragaloside IV Alleviates HCardiovascular therapeutics · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Hydrogen sulfide alleviates hypothyroidism-induced myocardial fibrosis in rats through stimulating autophagy and inhibiting TGF-β1/Smad2 pathway.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2023
    Article
  18. Review
  19. Article
  20. Astragaloside IV Ameliorates Isoprenaline-Induced Cardiac Fibrosis in MiceFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Li-Fei LuoDepartment of Physiology, School of Basic Medical Sciences, Hebei University of Chinese Medicine, Shijiazhuang, China.
Lu-Yun QinDepartment of Physiology, School of Basic Medical Sciences, Hebei University of Chinese Medicine, Shijiazhuang, China.
Jian-Xin WangDepartment of Physiology, School of Basic Medical Sciences, Hebei University of Chinese Medicine, Shijiazhuang, China.
Peng GuanDepartment of Physiology, School of Basic Medical Sciences, Hebei University of Chinese Medicine, Shijiazhuang, China.
Na WangDepartment of Physiology, School of Basic Medical Sciences, Hebei University of Chinese Medicine, Shijiazhuang, China.
En-Sheng JiDepartment of Physiology, School of Basic Medical Sciences, Hebei University of Chinese Medicine, Shijiazhuang, China.
Hebei University of Chinese Medicine · CNHebei Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Astragaloside IV (ASIV) is the main active component of

Indexed as

adriamycinapoptosisastragaloside IVautophagyheartoxidative stress

Identifiers

PMID34108879
PMCPMC8184095
OpenAlexW3165718610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.