ReviewThe ISME journal2021
Open challenges for microbial network construction and analysis.
Review in The ISME journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
120 citing papers in PubMed, 1 synthesis or guideline pooled it, 280 citations in OpenAlex.
- The microbial dark matter and "wanted list" in worldwide wastewater treatment plants.Microbiome · 2023Pooled it
- Differential co-occurrence analysis: a method to extract ecological modules from clinical microbiome data.mSystems · 2026Article
- Beyond detection: unveiling microbial dynamics in oak seedlings using fungal isolation and amplicon sequencing.Environmental microbiome · 2026Article
- Elevational Variation in Rhizosphere Bacterial Assembly and Fine-Scale Taxon Differentiation ofMicroorganisms · 2026Article
- Effects of ginger on microbial succession and flavor formation during Zao Chili fermentation.Food chemistry: X · 2026Article
- Evaluating microbial network inference methods: moving beyond synthetic data with reproducibility-driven benchmarks.BMC bioinformatics · 2026Article
- Breakdown of microbial networks links nutrient stress and reef coral disease.Nature communications · 2026Article
- A Tree-Based Model for Addressing Sparsity and Taxa Covariance in Microbiome Compositional Count Data.Statistics in medicine · 2026Article
- River Microbiomes as Sentinels of National-Scale Freshwater Ecosystems.Global change biology · 2026Article
- ABaCo: addressing heterogeneity challenges in metagenomic data integration with adversarial generative models.Nucleic acids research · 2026Article
- Reintroduction of Grassland Plant Species Shapes Soil Bacterial Ecological Groups and Contributes Differently To Bacterial Diversity.Microbial ecology · 2026Article
- Article
- Long vs. short read sequencing for microbial ecology of sedimentary environments: a case study from Lake Arnon, Switzerland.FEMS microbiology letters · 2026Article
- Improving DirectLiNGAM for high-dimensional microbiome data: roots screening and eBIC based model selection.Frontiers in systems biology · 2026Article
- Contrasting microbial iron metabolism in sediments from oxic and hypoxic estuaries.Frontiers in microbiology · 2026Article
- Effects of reduced nitrogen on the nifH-harboring soil microbiome in a soybean-maize strip intercropping system.Frontiers in microbiology · 2026Article
- Temperature Thresholds Govern Microbial-Mediated Dissolved Organic Carbon Dynamics in Coastal Ecosystems.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Stage-specific cyanobacterial handoffs and heterotrophic subsidies underpin biocrust carbon accumulation.ISME communications · 2026Article
- Bacterial community adaptation after brackish and freshwater coalescence.ISME communications · 2026Article
- MNetClass: a control-free microbial network clustering framework for identifying central subcommunities across ecological niches.mSystems · 2025Article
60 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbial network construction is a popular explorative data analysis technique in microbiome research. Although a large number of microbial network construction tools has been developed to date, there are several issues concerning the construction and interpretation of microbial networks that have received less attention. The purpose of this perspective is to draw attention to these underexplored challenges of microbial network construction and analysis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.