Evidence map›Paper›PMID 34108549›Full record

ArticleScientific reports2021

Repurposing CPAP machines as stripped-down ventilators.

J Nguyen, K Kesper, G Kräling, C Birk, P Mross, N Hofeditz, J Höchst, P Lampe, A Penning, B Leutenecker-Twelsiek and 11 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

J NguyenFaculty of Physics and Material Sciences Centre, Philipps-Universität Marburg, Marburg, Germany. johnny.nguyen@physik.uni-marburg.de.
K KesperDepartment of Pneumology, Philipps-Universität Marburg, Marburg, Germany.
G KrälingDepartment of Medical Technology, Universitätsklinikum Gießen und Marburg, Marburg, Germany.
C BirkFaculty of Physics and Material Sciences Centre, Philipps-Universität Marburg, Marburg, Germany.
P MrossDepartment of Neurology, Universitätsklinikum Gießen und Marburg, Marburg, Germany.
N HofeditzFaculty of Physics and Material Sciences Centre, Philipps-Universität Marburg, Marburg, Germany.
J HöchstFaculty of Mathematics and Computer Science, Philipps-Universität Marburg, Marburg, Germany.
P LampeFaculty of Mathematics and Computer Science, Philipps-Universität Marburg, Marburg, Germany.
A PenningFaculty of Mathematics and Computer Science, Philipps-Universität Marburg, Marburg, Germany.
B Leutenecker-TwelsiekTRUMPF, Ditzingen, Germany.
C SchindlerFaculty of Physics and Material Sciences Centre, Philipps-Universität Marburg, Marburg, Germany.
H BuchenauerSchneider GmbH & Co KG, Fronhausen, Germany.
D GeiselFaculty of Physics and Material Sciences Centre, Philipps-Universität Marburg, Marburg, Germany.
C SommerFaculty of Physics and Material Sciences Centre, Philipps-Universität Marburg, Marburg, Germany.
R HenningDepartment of Anaesthesiology & Intensive Care Medicine, Universitätsklinikum Gießen und Marburg, Marburg, Germany.
P WallotDepartment of Anaesthesiology & Intensive Care Medicine, Universitätsklinikum Gießen und Marburg, Marburg, Germany.
T WiesmannDepartment of Anaesthesiology & Intensive Care Medicine, Universitätsklinikum Gießen und Marburg, Marburg, Germany.
B BeutelDepartment of Medicine, Pulmonary and Critical Care Medicine, Universitätsklinikum Gießen und Marburg, Member of the German Centre for Lung Research (DZL), Marburg, Germany.
G SchneiderSchneider GmbH & Co KG, Fronhausen, Germany.
E Castro-CamusCentro de Investigaciones en Optica, A.C., Loma del Bosque 115, Lomas del Campestre, 37150, Leon, Guanajuato, Mexico.
M KochFaculty of Physics and Material Sciences Centre, Philipps-Universität Marburg, Marburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The worldwide shortage of medical-grade ventilators is a well-known issue, that has become one of the central topics during the COVID-19 pandemic. Given that these machines are expensive and have long lead times, one approach is to vacate them for patients in critical conditions while patients with mild to moderate symptoms are treated with stripped-down ventilators. We propose a mass-producible solution that can create such ventilators with minimum effort. The central part is a module that can be attached to CPAP machines and repurpose them as low-pressure ventilators. Here, we describe the concept and first measurements which underline the potential of our solution. Our approach may serve as a starting point for open-access ventilator technologies.

Identifiers

PMID34108549
PMCPMC8190155

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.