Evidence map›Paper›PMID 34108546›Full record

ArticleScientific reports2021

S100A9/CD163 expression profiles in classical monocytes as biomarkers to discriminate idiopathic pulmonary fibrosis from idiopathic nonspecific interstitial pneumonia.

Masahiro Yamashita, Yuh Utsumi, Hiromi Nagashima, Hiroo Nitanai, Kohei Yamauchi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Brain Resident Ly6CAging and disease · 2024
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Masahiro YamashitaDepartment of Pulmonary Medicine, Allergy and Immunological Diseases, Iwate Medical University School of Medicine, 1-1-1 Idaidouri, Yahabacho, Shiwa, 028-3694, Japan. yamam@iwate-med.ac.jp.
Yuh UtsumiDepartment of Pulmonary Medicine, Allergy and Immunological Diseases, Iwate Medical University School of Medicine, 1-1-1 Idaidouri, Yahabacho, Shiwa, 028-3694, Japan.
Hiromi NagashimaDepartment of Pulmonary Medicine, Allergy and Immunological Diseases, Iwate Medical University School of Medicine, 1-1-1 Idaidouri, Yahabacho, Shiwa, 028-3694, Japan.
Hiroo NitanaiDepartment of Pulmonary Medicine, Allergy and Immunological Diseases, Iwate Medical University School of Medicine, 1-1-1 Idaidouri, Yahabacho, Shiwa, 028-3694, Japan.
Kohei YamauchiDepartment of Pulmonary Medicine, Allergy and Immunological Diseases, Iwate Medical University School of Medicine, 1-1-1 Idaidouri, Yahabacho, Shiwa, 028-3694, Japan.
Iwate Medical University · JPNational Hospital Organization Hanamaki Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circulating monocytes have pathogenic relevance in idiopathic pulmonary fibrosis (IPF). Here, we determined whether the cell surface levels of two markers, pro-inflammatory-related S100A9 and anti-inflammatory-related CD163, expressed on CD14

Indexed as

AgedAntigens, CDAntigens, Differentiation, MyelomonocyticBiomarkersCalgranulin BCase-Control StudiesCD163 AntigenDiagnosis, DifferentialFemaleHumansIdiopathic Pulmonary FibrosisLung Diseases, InterstitialMaleMonocytesProspective StudiesReceptors, Cell SurfaceAntigens, CDAntigens, Differentiation, MyelomonocyticBiomarkersCalgranulin BCD163 AntigenReceptors, Cell SurfaceS100A9 protein, human

Identifiers

PMID34108546
PMCPMC8190107
OpenAlexW3170440674

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.