Evidence map›Paper›PMID 34108529›Full record

ArticleScientific reports2021

Small-scale dissolution test screening tool to select potentially substandard and falsified (SF) medicines requiring full pharmacopoeial analysis.

Mohammad Sofiqur Rahman, Naoko Yoshida, Hirohito Tsuboi, Yuichiro Ishii, Yoshio Akimoto, Kazuko Kimura

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Quality of Essential Medicines from Different Sources in Enugu and Anambra, Nigeria.The American journal of tropical medicine and hygiene · 2024
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammad Sofiqur Rahman *Medi-Quality Security Institute, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, 920-1192, Japan. rahmansofique@staff.kanazawa-u.ac.jp.
Naoko Yoshida *AI Hospital/Macro Signal Dynamics Research and Development Center, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.
Hirohito TsuboiDepartment of Clinical Pharmacy and Healthcare Sciences, Kanazawa University, Kanazawa, 920-1192, Japan. tsuboih@p.kanazawa-u.ac.jp.
Yuichiro IshiiDepartment of Clinical Pharmacy and Healthcare Sciences, Kanazawa University, Kanazawa, 920-1192, Japan.
Yoshio AkimotoMedi-Quality Security Institute, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, 920-1192, Japan.
Kazuko KimuraMedi-Quality Security Institute, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, 920-1192, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to design a convenient, small-scale dissolution test for extracting potential substandard and falsified (SF) medicines that require full pharmacopoeial analysis. The probability of metronidazole samples complying with the US Pharmacopoeia (USP) dissolution test for immediate-release tablet formulations was predicted from small-scale dissolution test results using the following criteria: (1) 95% confidence interval lower limit (95% CI

Identifiers

PMID34108529
PMCPMC8190288

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.