Evidence map›Paper›PMID 34108438›Full record

ArticleThe American journal of case reports2021

Surgical and Radiological Management of Complicated Uterine Leiomyoma Aided by 3D Models in a Patient with Fibrodysplasia Ossificans Progressiva.

Michelle Ho, Beau Y Park, Norman G Rosenblum, Mona Al Mukaddam, Frederick S Kaplan, Victor Kucherov, Scott G Hubosky, Gregory Kane, Vishal Desai, Michael R Kramer and 5 more

Open access · greenAbstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Michelle HoSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Beau Y ParkDepartment of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA, USA.
Norman G RosenblumDepartment of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA, USA.
Mona Al MukaddamDepartments of Medicine and Orthopedic Surgery, Center for Research in FOP and Related Disorders, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Frederick S KaplanDepartments of Medicine and Orthopedic Surgery, Center for Research in FOP and Related Disorders, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Victor KucherovDepartment of Urology, Thomas Jefferson University, Philadelphia, PA, USA.
Scott G HuboskyDepartment of Urology, Thomas Jefferson University, Philadelphia, PA, USA.
Gregory KaneDepartment of Medicine, Thomas Jefferson University, Philadelphia, PA, USA.
Vishal DesaiDepartment of Radiology, Thomas Jefferson University, Philadelphia, PA, USA.
Michael R KramerDepartment of Radiology, Thomas Jefferson University, Philadelphia, PA, USA.
Bon S KuHealth Design Lab, Thomas Jefferson University, Philadelphia, PA, USA.
Eric S SchwenkDepartment of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA.ORCID 0000-0003-3464-4149
Jaime L BarattaDepartment of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA.
Deepti HarshavardhanaDepartment of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA.
Zvi GrunwaldDepartment of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA.
Thomas Jefferson University · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disorder of the connective tissue. Over time, patients with FOP experience decreased range of motion in the joints and the formation of a second skeleton, limiting mobility. Patients with FOP are advised to avoid any unwarranted surgery owing to the risk of a heterotopic ossification flare-up. For patients who do require a surgical procedure, a multidisciplinary team is recommended for comprehensive management of the patient's needs. CASE REPORT A 27-year-old woman with FOP underwent a hysterectomy for removal of a suspected necrotic uterine fibroid. To aid in presurgical planning and management, patient-specific 3-dimensional (3D) models of the patient's tracheobronchial tree, thorax, and lumbosacral spine were printed from the patient's preoperative computed tomography (CT) imaging. The patient required awake nasal fiberoptic intubation for general anesthesia and transversus abdominus plane block for regional anesthesia. Other anesthesia modalities, including spinal epidural, were ruled out after visualizing the patient's anatomy using the 3D model. Postoperatively, the patient was started on a multi-modal analgesic regimen and a course of steroids, and early ambulation was encouraged. CONCLUSIONS Patients with FOP are high-risk surgical patients requiring the care of multiple specialties. Advanced visualization methods, including 3D printing, can be used to better understand their anatomy and locations of heterotopic bone ossification that can affect patient positioning. Our patient successfully underwent supracervical hysterectomy and bilateral salpingectomy with no signs of fever or sepsis at follow-up.

Indexed as

LeiomyomaMyositis OssificansOssification, HeterotopicAdultFemaleHumansIntubation, IntratrachealRadiography

Identifiers

PMID34108438
PMCPMC8207543
OpenAlexW3163867244

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.