Evidence map›Paper›PMID 34108340›Full record

ArticleThe Journal of veterinary medical science2021

Effect of lactoferrin on murine embryo development created from lipopolysaccharide-treated sperm.

Takahiro Aya, Yukiko Tomioka, Takashi Takeuchi

Open access · diamondAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Takahiro AyaDepartment of Laboratory Animal Science, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan.
Yukiko TomiokaDepartment of Laboratory Animal Science, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan.
Takashi TakeuchiDepartment of Laboratory Animal Science, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan.
Tottori University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of lactoferrin (LF) on embryo development was investigated by using lipopolysaccharide (LPS)-treated mouse sperm. For the development rate of the 2-cell stage embryo, the embryo derived from LPS- and LF-treated sperm showed similar survival rate to the control embryo. On day 12 after the embryo transfer into the recipient, the frequent abnormality was observed in the embryo derived from LPS-treated sperm, and the abnormality was tended to be inhibited in the embryo derived from LPS- and LF-treated sperm. These results imply that LF treatment on sperm contaminated with bacteria may facilitate the embryo development, which contribute to the improvement of infertility.

Indexed as

LactoferrinLipopolysaccharidesAnimalsEmbryonic DevelopmentMaleMiceSpermatozoaLactoferrinLipopolysaccharidesbacteriainfertilitylactoferrinspermToll-like receptor

Identifiers

PMID34108340
PMCPMC8349819
OpenAlexW3167996694

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.