Evidence map›Paper›PMID 34108336›Full record

ArticleThe Journal of veterinary medical science2021

Anaphylaxis after rabies vaccination for dogs in Japan.

Megumi Yoshida, Keijiro Mizukami, Masaharu Hisasue, Ichiro Imanishi, Keigo Kurata, Masaki Ochiai, Masato Itoh, Tadahiro Nasukawa, Jumpei Uchiyama, Hajime Tsujimoto and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of veterinary medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Anaphylaxis after vaccination for cats in Japan.The Journal of veterinary medical science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Megumi YoshidaLaboratory of Veterinary Microbiology I, Azabu University, Sagamihara, Kanagawa 252-5201, Japan.
Keijiro MizukamiLaboratory of Veterinary Microbiology I, Azabu University, Sagamihara, Kanagawa 252-5201, Japan.
Masaharu HisasueLaboratory of Small Animal Internal Medicine, Azabu University, Sagamihara, Kanagawa 252-5201, Japan.
Ichiro ImanishiDepartment of Microbiology, Kitasato University School of Medicine, Sagamihara, Kanagawa 252-0329, Japan.
Keigo KurataITEA Inc., Institute of Tokyo Environmental Allergy, Bunkyo-ku, Tokyo 113-0034, Japan.
Masaki OchiaiDepartment of Quality Assurance Radiation Safety, and Information Management, National Institute of Infectious Diseases, Musashimurayama, Tokyo 208-0011, Japan.
Masato ItohLaboratory of Veterinary Microbiology I, Azabu University, Sagamihara, Kanagawa 252-5201, Japan.
Tadahiro NasukawaLaboratory of Veterinary Microbiology I, Azabu University, Sagamihara, Kanagawa 252-5201, Japan.
Jumpei UchiyamaLaboratory of Veterinary Microbiology I, Azabu University, Sagamihara, Kanagawa 252-5201, Japan.
Hajime TsujimotoDepartment of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Masahiro SakaguchiLaboratory of Veterinary Microbiology I, Azabu University, Sagamihara, Kanagawa 252-5201, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe adverse reactions after rabies vaccination in dogs were examined from 317 cases reported to the Ministry of Agriculture, Forestry and Fisheries (MAFF) in Japan during 15-year period from April 2004 to March 2019. We found that 109 of the 317 dogs showed anaphylaxis (0.15/100,000 vaccinated dogs), and 71 of the 109 cases of anaphylaxis resulted in death (0.10/100,000 vaccinated dogs). We measured bovine serum albumin (BSA) in four commercially available rabies vaccines and found the levels ranged from 0.1 to 16.6 µg/dose. Our survey showed that the rate of anaphylaxis to rabies vaccines in dogs is rare, although some cases of anaphylaxis resulted in death. Veterinarians should be well prepared to deal with vaccine-associated anaphylaxis.

Indexed as

AnaphylaxisDog DiseasesRabiesRabies VaccinesAnimalsDogsJapanVaccinationRabies Vaccinesadverse reactionanaphylaxisdograbies vaccine

Identifiers

PMID34108336
PMCPMC8437711

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.