Evidence map›Paper›PMID 34108244›Full record

ReviewPractical neurology2021

Trigeminal neuralgia: a practical guide.

Giorgio Lambru, Joanna Zakrzewska, Manjit Matharu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Practical neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giorgio LambruThe Headache Service, Pain Management and Neuromodulation Centre, Guy's and St Thomas' Hospitals NHS Trust, London, UK.
Joanna ZakrzewskaFacial Pain Clinic, Eastman Dental Hospital, London, UK.
Manjit MatharuHeadache and Facial Pain Group, UCL Queen Square Institute of Neurology, London, UK manjit.matharu@nhs.net.ORCID http://orcid.org/0000-0002-4960-2294

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trigeminal neuralgia (TN) is a highly disabling disorder characterised by very severe, brief and electric shock like recurrent episodes of facial pain. New diagnostic criteria, which subclassify TN on the basis of presence of trigeminal neurovascular conflict or an underlying neurological disorder, should be used as they allow better characterisation of patients and help in decision-making regarding medical and surgical treatments. MR imaging, including high-resolution trigeminal sequences, should be performed as part of the diagnostic work-up. Carbamazepine and oxcarbazepine are drugs of first choice. Lamotrigine, gabapentin, pregabalin, botulinum toxin type A and baclofen can be used either alone or as add-on therapy. Surgery should be considered if the pain is poorly controlled or the medical treatments are poorly tolerated. Trigeminal microvascular decompression is the first-line surgery in patients with trigeminal neurovascular conflict while neuroablative surgical treatments can be offered if MR imaging does not show any neurovascular contact or where patients are considered too frail for microvascular decompression or do not wish to take the risk.

Indexed as

Trigeminal NeuralgiaAnticonvulsantsCarbamazepineHumansMagnetic Resonance ImagingOxcarbazepineAnticonvulsantsCarbamazepineOxcarbazepineheadachepaintrigeminal nervetrigeminal neuralgia

Identifiers

PMID34108244
PMCPMC8461413

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.