ArticleBMJ open2021
Evaluation of risk mitigation measures for people with substance use disorders to address the dual public health crises of COVID-19 and overdose in British Columbia: a mixed-method study protocol.
Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- The characteristics and experiences of parents accessing prescribed safer supply in BC, 2020-2021.Harm reduction journal · 2026Article
- Clinicians' Perspectives and an Ethical Analysis of Safer Supply Opioid Prescribing.Journal of bioethical inquiry · 2025Article
- Preferred pharmaceutical-grade opioids to reduce the use of unregulated opioids: A cross-sectional analysis among people who use unregulated opioids in Vancouver, Canada.The International journal on drug policy · 2024Article
- Access and barriers to safer supply prescribing during a toxic drug emergency: a mixed methods study of implementation in British Columbia, Canada.Substance abuse treatment, prevention, and policy · 2024Article
- "If it wasn't for them, I don't think I would be here": experiences of the first year of a safer supply program during the dual public health emergencies of COVID-19 and the drug toxicity crisis.Harm reduction journal · 2024Article
- Implementation of pharmaceutical alternatives to a toxic drug supply in British Columbia: A mixed methods study.Journal of substance use and addiction treatment · 2024Article
- Opioid Coprescription Through Risk Mitigation Guidance and Opioid Agonist Treatment Receipt.JAMA network open · 2024Article
- Effect of Risk Mitigation Guidance opioid and stimulant dispensations on mortality and acute care visits during dual public health emergencies: retrospective cohort study.BMJ (Clinical research ed.) · 2024Article
- Factors associated with obtaining prescribed safer supply among people accessing harm reduction services: findings from a cross-sectional survey.Harm reduction journal · 2024Article
- Influence of physician networks on the implementation of pharmaceutical alternatives to a toxic drug supply in British Columbia.Implementation science : IS · 2024Article
- Neonatal abstinence syndrome and infant mortality and morbidity: a population-based study.Frontiers in pediatrics · 2024Article
- Developing a Theoretically Informed Implementation Model for Telemedicine-Delivered Medication for Opioid Use Disorder: Qualitative Study With Key Informants.JMIR mental health · 2023Article
- Doing community-based research during dual public health emergencies (COVID and overdose).Harm reduction journal · 2023Article
- Article
- Incorporating prescription psychostimulants into the continuum of care for people with stimulant use disorder in Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023Article
- Changes in daily dose in open-label compared to double-blind: The role of clients' expectations in injectable opioid agonist treatment.Addictive behaviors reports · 2023Article
- Smoking identified as preferred mode of opioid safe supply use; investigating correlates of smoking preference through a 2021 cross-sectional study in British Columbia.Substance abuse treatment, prevention, and policy · 2023Article
- Stimulant Use and Chronic Cardiovascular Disease: Increasing Urgency of Intervention in the Context of a Toxic Illicit Drug Supply.Journal of general internal medicine · 2023Article
- Substance use disorders and COVID-19: reflections on international research and practice changes during the "poly-crisis".Frontiers in public health · 2023Article
- Stimulant use disorder diagnosis and opioid agonist treatment dispensation following release from prison: a cohort study.Substance abuse treatment, prevention, and policy · 2022Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe COVID-19 pandemic was preceded by an ongoing overdose crisis and linked to escalating drug overdose deaths in British Columbia (BC). At the outset of these dual public health emergencies, the BC government announced interim Risk Mitigation Guidance (RMG) that permitted prescribing medication alternatives to substances, including opioids, alcohol, stimulants and benzodiazepines, an intervention sometimes referred to as 'safe supply'. This protocol outlines the approach for a study of the implementation of RMG and its impacts on COVID-19 infection, drug-related and systemic harms, continuity of care for people with substance use disorder (SUD), as well as their behavioural, psychosocial and well-being outcomes. METHODS AND ANALYSIS: We conducted a parallel mixed-method study that involved both analysis of population-level administrative health data and primary data collection, including a 10-week longitudinal observational study (target n=200), a cross-sectional survey (target n=200) and qualitative interviews (target n=60). We implemented a participatory approach to this evaluation, partnering with people with lived or living expertise of drug use, and researchers and public health decision-makers across the province. Linked population-level administrative databases will analyse data from a cohort of BC residents with an indication of SUD between 1996 and 2020. We will execute high-dimensional propensity score matching and marginal structural modelling to construct a control group and to assess the impact of RMG dispensation receipt on a collaboratively determined set of primary and secondary outcomes. ETHICS AND DISSEMINATION: Study activities were developed to adhere to the Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans, recommended COVID-19 research practices, and guided by the Truth and Reconciliation Commission's Calls to Action for public health, data governance and research ethics related to Indigenous people. Results will be disseminated incrementally, on an ongoing basis, through the consortium established for this study, then published in peer-reviewed journals.
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