Evidence map›Paper›PMID 34108163›Full record

ArticleBMJ open2021

Effect of tourniquet use on the risk of revision in total knee replacement surgery: an analysis of the National Joint Registry Data Set.

Muhamed M Farhan-Alanie, Yujin Lee, Martin Underwood, Andrew Metcalfe, Mark J Wilkinson, Andrew James Price, Jane Warwick, Peter David Henry Wall

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Observational
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Muhamed M Farhan-AlanieClinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK muhamed.farhan-alanie@nhs.net.ORCID 0000-0002-9209-0108
Yujin LeeClinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
Martin UnderwoodClinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
Andrew MetcalfeClinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.ORCID 0000-0002-4515-8202
Mark J WilkinsonDepartment of Oncology and Metabolism, The University of Sheffield, Sheffield, UK.ORCID 0000-0001-5577-3674
Andrew James PriceNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Jane WarwickClinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
Peter David Henry WallClinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.ORCID 0000-0003-3149-3373
University Hospitals Coventry and Warwickshire NHS Trust · GBUniversity of Warwick · GBNuffield Orthopaedic Centre · GBUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTourniquet use in total knee replacement (TKR) is believed to improve the bone-cement interface by reducing bleeding, potentially prolonging implant survival. This study aimed to compare the risk of revision for primary cemented TKR performed with or without a tourniquet.

designWe analysed data from the National Joint Registry (NJR) for all primary cemented TKRs performed in England and Wales between April 2003 and December 2003. Kaplan-Meier plots and Cox regression were used to assess the influence of tourniquet use, age at time of surgery, sex and American Society of Anaesthesiologists (ASA) classification on risk of revision for all-causes.

resultsData were available for 16 974 cases of primary cemented TKR, of which 16 132 had surgery with a tourniquet and 842 had surgery without a tourniquet. At 10 years, 3.8% had undergone revision (95% CI 2.6% to 5.5%) in the no-tourniquet group and 3.1% in the tourniquet group (95% CI 2.8% to 3.4%). After adjusting for age at primary surgery, gender and primary ASA score, the HR for all-cause revision for cemented TKR without a tourniquet was 0.82 (95% CI 0.57 to 1.18).

conclusionsWe did not find evidence that using a tourniquet for primary cemented TKR offers a clinically important or statistically significant reduction in the risk of all-cause revision up to 13 years after surgery. Surgeons should consider this evidence when deciding whether to use a tourniquet for cemented TKR.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisEnglandHumansProsthesis FailureRegistriesReoperationTourniquetsWalesadult orthopaedicskneelimb reconstructionorthopaedic & trauma surgery

Identifiers

PMID34108163
PMCPMC8191625
OpenAlexW3170241854

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.