Evidence map›Paper›PMID 34107593›Full record

ReviewZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2021

[Advances in research on the relationship between bile acid, gut microbiota and the occurrence and development of cholangiocarcinoma].

H Sang, W J Li, Y Zhou, H Zhu

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

H SangDepartment of Gastroenterology, the First Affiliated Hospital With Nanjing Medical University, Nanjing 210029, China.
W J LiDepartment of Gastroenterology, the First Affiliated Hospital With Nanjing Medical University, Nanjing 210029, China.
Y ZhouDepartment of Gastroenterology, the First Affiliated Hospital With Nanjing Medical University, Nanjing 210029, China.
H ZhuDepartment of Gastroenterology, the First Affiliated Hospital With Nanjing Medical University, Nanjing 210029, China.
Nanjing Medical University · CN

Funding

"333" Project in Jiangsu Province LGY2016010Nanjing Science and Technology Bureau Project 201715003Six Talent Peaks in Jiangsu Province WSN-030
6 · The paper itself

Abstract

Cholangiocarcinoma is a kind of malignant tumor that originates from the bile duct epithelium. Due to its insidious nature, there is no effective early diagnosis and treatment method. Therefore, once it is detected, it is at an advanced stage and has a poor prognosis. Bile acid is the main component of bile, which acts on cholangiocytes through bile acid receptors and plays a key role in the development of cholangiocarcinoma. Gut microbiota can participate in the occurrence of cholangiocarcinoma by regulating bile acid metabolism. This review mainly focuses on the role of bile acid and bile acid receptors in the occurrence and development of cholangiocarcinoma and the impact of gut microbiota in it.

Indexed as

Bile Duct NeoplasmsCholangiocarcinomaGastrointestinal MicrobiomeBile Acids and SaltsBile Ducts, IntrahepaticHumansBile Acids and SaltsBile acidBile acid receptorsCholangiocarcinomaIntestinal microorganism

Identifiers

PMID34107593
PMCPMC12814814
OpenAlexW3165985590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.