Trial reportApplied clinical informatics2021
Health Information Exchange between Specialists and General Practitioners Benefits Rural Patients.
Trial report in Applied clinical informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Can integrated care interventions strengthen primary care and improve outcomes for patients with chronic diseases? A systematic review and meta-analysis.Health research policy and systems · 2025Pooled it
- Improving Patient-Reported Outcomes in Stroke Care using Remote Blood Pressure Monitoring and Telehealth.Applied clinical informatics · 2023Trial
- Evaluation of an interdisciplinary electronic consultation service between general practitioners and medical specialists in The Netherlands: a prospective cohort study.Family practice · 2026Article
- Influences on Emergency Clinician Use of Health Information Exchange: Interview Study.JMIR medical informatics · 2025Article
- Health Information Exchange Usage in Japan: Content Analysis of Audit Logs.JMIR medical informatics · 2025Article
- Health Care Worker Usage of Large-Scale Health Information Exchanges in Japan: User-Level Audit Log Analysis Study.JMIR medical informatics · 2024Article
- Hidden systems in primary care cancer detection: an embedded qualitative intervention development study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2024Article
- Rurality, Cardiovascular Risk Factors, and Early Cardiovascular Disease among Childhood, Adolescent, and Young Adult Cancer Survivors.Research square · 2024Article
- Implementation of a Patient Summary Web Application According to the International Patient Summary and Validation in Common Use Cases in Japan.Journal of medical systems · 2023Article
- Assessing the effect of electronic health information exchange on the completeness and validity of data for measuring viral load testing turnaround time in Nigeria.International journal of medical informatics · 2023Article
- Rural, Large Town, and Urban Differences in Optimal Subspecialty Follow-up and Survivorship Care Plan Documentation among Childhood Cancer Survivors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023Article
- Depression in primary care and the role of evidence-based guidelines: cross-sectional data from primary care physicians in Germany.BMC health services research · 2022Article
- Evaluation of a Health Information Exchange System for Geriatric Health Care in Rural Areas: Development and Technical Acceptance Study.JMIR human factors · 2022Article
- Findings from the 2022 Yearbook Section on Health Information Exchange.Yearbook of medical informatics · 2022Review
- Hemodialysis Record Sharing: Solution for Work Burden Reduction and Disaster Preparedness.JMIR formative research · 2022Article
- Reporting Outcomes of Pediatric Intensive Care Unit Patients to Referring Physicians via an Electronic Health Record-Based Feedback System.Applied clinical informatics · 2022Article
- Patient-Centered Data Home: A Path Towards National Interoperability.Frontiers in digital health · 2022Article
- Can Prehospital Data Improve Early Identification of Sepsis in Emergency Department? An Integrative Review of Machine Learning Approaches.Applied clinical informatics · 2022Review
- The Impact of Community Health Information Exchange Usage on Time to Reutilization of Hospital Services.Annals of family medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHealth information exchange (HIE) may improve diagnostic accuracy, treatment efficacy, and safety by providing treating physicians with expert advice. However, most previous studies on HIE have been observational in nature.
objectivesTo examine whether collaboration between specialists and general practitioners (GPs) in rural areas via HIE can improve outcomes among patients at low-to-moderate risk of cardiovascular disease, kidney disease, and stroke.
methodsIn this randomized controlled trial, the Miyagi Medical and Welfare Information Network was used for HIE. We evaluated the clinical data of 1,092 patients aged ≥65 years living in the rural areas of the Miyagi Prefecture and receiving care from GPs only. High-risk patients were immediately referred to specialists, whereas low-to-moderate risk patients were randomly assigned to an intervention group in which GPs were advised by specialists through HIE (
resultsIn the intention-to-treat analysis, all-cause mortality and cumulative incidence of serious adverse events (e.g., hospital admission or unexpected referral to specialists) did not differ between the groups. However, per-protocol analysis controlling for GP adherence with specialist recommendations revealed significantly reduced all-cause mortality (
conclusionHIE systems may improve outcomes among low-to-moderate risk patients by promoting greater collaboration between specialists and GPs, particularly in rural areas with few local specialists.
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