ReviewJournal of affective disorders2021
Association between perceived stress and depression among medical students during the outbreak of COVID-19: The mediating role of insomnia.
Review in Journal of affective disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 2 of them syntheses that pooled it.
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Who cites it
83 citing papers in PubMed, 2 syntheses or guidelines pooled it, 131 citations in OpenAlex.
- The impact of COVID-19 on students' anxiety and its clarification: a systematic review.Frontiers in psychology · 2023Pooled it
- COVID-19 and mental health: A systematic review of international medical student surveys.Frontiers in psychology · 2022Pooled it
- Impact of learning environment on reading anxiety: a study of medical students in online and traditional settings.BMC medical education · 2024Trial
- The Effects of a Single Vagus Nerve's Neurodynamics on Heart Rate Variability in Chronic Stress: A Randomized Controlled Trial.Sensors (Basel, Switzerland) · 2024Trial
- Effect of Perceived Stress on Sleep Procrastination in College Students: A Chain-Mediated Role Between Depression and Inhibitory Control.Behavioral sciences (Basel, Switzerland) · 2026Article
- Perceived Sleep Quality as a Mediator Between Occupational Stress and Depression: The Moderating Role of Work Engagement.Journal of Korean medical science · 2026Article
- [Bidirectional longitudinal associations of perceived stress with anxiety and depressive symptoms among medical students: A threeZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Article
- Perceived Stress and Depressive Symptoms in Urban Chinese Women: The Buffering and Exacerbating Roles of Marital Quality.Healthcare (Basel, Switzerland) · 2026Article
- Perceived stress, stress-related symptoms, and support-based coping in healthcare students: insights from a cross-sectional study in the United Arab Emirates.BMC medical education · 2026Article
- The relationship between perceived stress, psychological resilience, and depressive symptoms in college students, and the moderating role of gender.Scientific reports · 2026Article
- Personality Trait Dimensions and Depressive Symptoms Among Medical Students: Sequential Mediation Through Psychological Capital and Perceived Stress.Depression and anxiety · 2026Article
- Perceived stress and depression in Chinese university students: a parallel mediation analysis examining the roles of insomnia and somatic symptoms.Frontiers in psychology · 2026Article
- The relationships among trauma, stress, social support, and psychopathology: exploring early warning factors of mental illness from a network analysis perspective.BMC psychology · 2025Article
- Chronotype and Depression: Serial Mediation of Perceived Stress and Insomnia in a Two-Wave Three-Month Longitudinal Study.The Psychiatric quarterly · 2025Article
- Factors related to quality of life in caregivers of children with autism spectrum disorder: emphasizing challenges in the context of Eastern China.BMC public health · 2025Article
- Comparing Insomnia and Perceived Stress in Online vs. Frontal Learning: Psychometric Evaluation in a Health Sciences Cohort.Healthcare (Basel, Switzerland) · 2025Article
- Baseline perceived stress as a predictor of ketamine/esketamine treatment response in treatment-resistant depression.Journal of affective disorders · 2025Article
- Impact of Perceived Unfairness, Uncertainty, and Life Stress on Urban Residents' Health in China: Cross-Sectional Study.JMIR public health and surveillance · 2025Article
- Interconnected struggles: How insomnia, anxiety, and depression impact mental health.World journal of psychiatry · 2025Article
- Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to explore the association between perceived stress and depression among medical students and the mediating role of insomnia in this relationship during the COVID-19 pandemic in China.
methodsA cross-sectional survey was conducted from March to April 2020 in medical university. Levels of perceived stress, insomnia and depression were measured using Perceived Stress Scale (PSS), Insomnia Severity Index (ISI) and Patient Health Questionnaire 9 (PHQ-9). The descriptive analyses of the demographic characteristics and correlation analyses of the three variables were calculated. The significance of the mediation effect was obtained using a bootstrap approach with SPSS PROCESS macro.
resultsThe mean age of medical students was 21.46 years (SD=2.50). Of these medical students, 10,185 (34.3%) were male and 19,478 (65.7%) were female. Perceived stress was significantly associated with depression (β=0.513, P < 0.001). Insomnia mediated the association between perceived stress and depression (β=0.513, P < 0.001). The results of the non-parametric bootstrapping method confirmed the significance of the indirect effect of perceived stress through insomnia (95% bootstrap CI =0.137, 0.149). The indirect effect of insomnia accounted for 44.13% of the total variance in depression.
conclusionsThese findings contribute to a better understanding of the interactive mechanisms underlying perceived stress and depression, and elucidating the mediating effects of insomnia on the association. This research provides a useful theoretical and methodological approach for prevention of depression in medical students. Findings from this study indicated that it may be effective to reduce depression among medical students by improving sleep quality and easing perceived stress.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.