ArticleJournal of affective disorders2021
Hand gesture performance is impaired in major depressive disorder: A matter of working memory performance?
Article in Journal of affective disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Gesture deficits in psychosis and the combination of group psychotherapy and transcranial magnetic stimulation: A randomized clinical trial.Molecular psychiatry · 2025Trial
- Psychomotor semiology in depression: a standardized clinical psychomotor approach.BMC psychiatry · 2022Trial
- Aberrant gesture use in autism spectrum disorders is unrelated to motor abnormalities.European archives of psychiatry and clinical neuroscience · 2026Article
- Transdiagnostic associations between subjective gesture behaviour and objective performance in schizophrenia and depression.Translational psychiatry · 2026Article
- Disorganisation and depression: a re-examination of how we think and speak when depressed.European archives of psychiatry and clinical neuroscience · 2026Review
- Automatic quantification of hand gestures in current and remitted Major Depressive Disorder during oral expression.Journal of affective disorders · 2025Article
- Motor actions across psychiatric disorders: A research domain criteria (RDoC) perspective.Clinical psychology review · 2024Review
- Apraxia: From Neuroanatomical Pathways to Clinical Manifestations.Current neurology and neuroscience reports · 2024Review
- Self-reported Gesture Interpretation and Performance Deficits in Individuals at Clinical High Risk for Psychosis.Schizophrenia bulletin · 2023Article
- Using virtual reality to assess gesture performance deficits in schizophrenia patients.Frontiers in psychiatry · 2023Article
- Motor Behavior is Relevant for Understanding Mechanism, Bolstering Prediction, And Improving Treatment: A Transdiagnostic Perspective.Schizophrenia bulletin · 2022Article
- Using dynamic point light display stimuli to assess gesture deficits in schizophrenia.Schizophrenia research. Cognition · 2022Article
- Brain Stimulation and Group Therapy to Improve Gesture and Social Skills in Schizophrenia-The Study Protocol of a Randomized, Sham-Controlled, Three-Arm, Double-Blind Trial.Frontiers in psychiatry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveIndividuals with depression exhibit numerous interpersonal deficits. As effective use of gestures is critical for social communication, it is possible that depressed individuals' interpersonal deficits may be due to deficits in gesture performance. The present study thus compared gesture performance of depressed patients and controls and examined whether these deficits relate to cognitive and other domains of dysfunction.
methodsGesture performance was evaluated in 30 depressed patients and 30 controls using the Test of Upper Limb Apraxia (TULIA). Clinical rating scales were assessed to determine if gesture deficits were associated with motor, cognitive or functional outcomes.
resultsCompared to controls, depressed patients exhibited impaired gesture performance with 2/3 of the patients demonstrating gesture deficits. Within depressed patients, gesture performance was highly correlated with working memory abilities. In contrast, no association between gesture performance and gestural knowledge, psychomotor retardation, depression severity, or frontal dysfunction was observed in patients. LIMITATIONS: This is a cross-sectional study and a larger size would have allowed for confident detection of more subtle, but potentially relevant effects.
conclusionGesture performance is impaired in depressed patients, and appears to be related to poor working memory abilities, suggesting a disruption in the retrieval of gestural cues indicative of a distinct clinical phenomenon that might be related to social functioning.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.