Evidence map›Paper›PMID 34107326›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2021

SARS-CoV-2 reinfection with a virus harboring mutation in the Spike and the Nucleocapsid proteins in Panama.

Yamilka Díaz, Anyuri Ortiz, Adriana Weeden, Daniel Castillo, Claudia González, Brechla Moreno, Mabel Martínez-Montero, Marlene Castillo, Grettel Vasquez, Lisseth Sáenz and 24 more

Erratum issuedOpen access · goldAbstract readCase Reports
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Reinfection in patients with COVID-19: a systematic review.Global health research and policy · 2022
    Pooled it
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  11. Occurrence of SARS-CoV-2 reinfections at regular intervals in Ecuador.Frontiers in cellular and infection microbiology · 2022
    Article
  12. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors at 1 institution in 1 country.

Yamilka DíazDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Anyuri OrtizDepartment of Occupational Health, Gorgas Memorial Institute of Health Studies, Panama.
Adriana WeedenUnit of Diagnosis, Clinical Research and Tropical Medicine, Gorgas Memorial Institute of Health Studies, Panama.
Daniel CastilloDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Claudia GonzálezDepartment of Genomic and Proteomic, Gorgas Memorial Institute of Health Studies, Panama.
Brechla MorenoDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Mabel Martínez-MonteroImmunovirology Division, Public Health Reference Central Laboratory, Gorgas Memorial Institute of Health Studies, Panama.
Marlene CastilloDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Grettel VasquezDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Lisseth SáenzDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Danilo FrancoDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Yaneth PittiDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Oris ChavarriaDepartment of Genomic and Proteomic, Gorgas Memorial Institute of Health Studies, Panama.
Jessica GondolaDepartment of Genomic and Proteomic, Gorgas Memorial Institute of Health Studies, Panama.
Ambar M MorenoDepartment of Genomic and Proteomic, Gorgas Memorial Institute of Health Studies, Panama.
Leyda ÁbregoDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Davis BeltránDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Ilka GuerraDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Jim ChangDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Zumara ChaverraDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Isela GuerreroDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Alejandra ValoyDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Melissa GaitánDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Dimelza AraúzDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Ernesto MoránDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Maria Chen-GermánDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Elimelec ValdespinoDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Rita RodríguezDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Rita CorralesDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Roderick Chen-CamañoDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama.
Juan Miguel PascaleUnit of Diagnosis, Clinical Research and Tropical Medicine, Gorgas Memorial Institute of Health Studies, Panama.
Alexander A MartínezDepartment of Genomic and Proteomic, Gorgas Memorial Institute of Health Studies, Panama. Electronic address: almartinez@gorgas.gob.pa.
Sandra López-VergèsDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama. Electronic address: slopez@gorgas.gob.pa.
Gorgas COVID19 Team
Instituto Conmemorativo Gorgas de Estudios de la Salud · PA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of reinfection by SARS-CoV-2 with the second virus harboring amino acid changes in the Spike protein (141-143del, D215A, ins215AGY, L452R, D614G), orf1a, helicase, orf3a, and Nucleocapside. The virus associated with the reinfection, from an endemic lineage containing the S:L452R immune escape mutation, was circulating in Panama at the time.

Indexed as

COVID-19SARS-CoV-2HumansMutationNucleocapsid ProteinsReinfectionSpike Glycoprotein, CoronavirusNucleocapsid ProteinsSpike Glycoprotein, CoronavirusCOVID-19MutationPanamaReinfectionSARS-CoV-2

Identifiers

PMID34107326
PMCPMC8180085
OpenAlexW3170704515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.