Evidence map›Paper›PMID 34107243›Full record

ReviewStem cell reports2021

Unproven stem cell interventions: A global public health problem requiring global deliberation.

Zubin Master, Kirstin R W Matthews, Mohamed Abou-El-Enein

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Stem cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  12. Genes drive organisms and slippery slopes.Pathogens and global health · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Zubin MasterBiomedical Ethics Research Program and the Center for Regenerative Medicine, Mayo Clinic, Rochester, MN, USA. Electronic address: master.zubin@mayo.edu.
Kirstin R W MatthewsBaker Institute for Public Policy Center for Health and Biosciences, Rice University, Houston, TX, USA.
Mohamed Abou-El-EneinDivision of Medical Oncology, Department of Medicine, and Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Joint USC/CHLA Cell Therapy Program, University of Southern California, and Children Hospital Los Angeles, Los Angeles, CA, USA. Electronic address: abouelenein@med.usc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The unproven stem cell intervention (SCI) industry is a global health problem. Despite efforts of some nations, the industry continues to flourish. In this paper, we call for a global approach and the establishment of a World Health Organization (WHO) Expert Advisory Committee on Regenerative Medicine to tackle this issue and provide guidance. The WHO committee can harmonize national regulations; promote regulatory approaches responsive to unmet patient needs; and formulate an education campaign against misinformation. Fostering an international dialog and developing recommendations that can be adopted by member states would effectively address the global market of unproven SCIs.

Indexed as

Government RegulationHealth PolicyHumansPublic HealthRegenerative MedicineStem Cell TransplantationWorld Health Organizationglobal healthpatient viewsregenerative medicineregulationsunproven stem cell interventionsWorld Health Organization

Identifiers

PMID34107243
PMCPMC8190665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.