ArticlePloS one2021
Brain responsivity to emotional faces differs in men and women with and without a history of alcohol use disorder.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Alcohol misuse and negative emotion processing in neurotypical drinkers: Sex differences in behavioral and neural markers.Psychiatry research. Neuroimaging · 2026Article
- Alcohol Cues Elicit Differences in Brain Activation Patterns of Abstinent Men and Women with Alcohol Use Disorders.Neuropsychiatric disease and treatment · 2026Article
- The effects of polygenic risks for alcohol misuse on negative emotion processing in young adult binge drinkers.Translational psychiatry · 2025Article
- Sex differences in alcohol's effects on fronto-amygdalar functional connectivity during processing of emotional stimuli.Alcohol, clinical & experimental research · 2024Article
- A systematic review of sex/gender differences in the multi-dimensional neurobiological mechanisms in addiction and their relevance to impulsivity.Current addiction reports · 2023Article
- Anterior cingulate metabolite levels, memory, and inhibitory control in abstinent men and women with alcohol use disorder.Alcohol and alcoholism (Oxford, Oxfordshire) · 2023Article
- Decoding Emotion in Drug Abusers: Evidence for Face and Body Emotion Recognition and for Disgust Emotion.European journal of investigation in health, psychology and education · 2022Article
- High-Risk Drinkers Engage Distinct Stress-Predictive Brain Networks.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Article
- Intrinsic brain functional connectivity patterns in alcohol use disorder.Brain communications · 2022Article
- Hippocampal subfield volumes in abstinent men and women with a history of alcohol use disorder.PloS one · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Inclusion of women in research on Alcohol Use Disorder (AUD) has shown that gender differences contribute to unique profiles of cognitive, emotional, and neuropsychological dysfunction. We employed functional magnetic resonance imaging (fMRI) of abstinent individuals with a history of AUD (21 women [AUDw], 21 men [AUDm]) and demographically similar non-AUD control (NC) participants without AUD (21 women [NCw], 21 men [NCm]) to explore how gender and AUD interact to influence brain responses during emotional processing and memory. Participants completed a delayed match-to-sample emotional face memory fMRI task, and brain activation contrasts between a fixation stimulus and pictures of emotional face elicited a similar overall pattern of activation for all four groups. Significant Group by Gender interactions revealed two activation clusters. A cluster in an anterior portion of the middle and superior temporal gyrus, elicited lower activation to the fixation stimulus than to faces for the AUDw as compared to the NCw; that abnormality was more pronounced than the one observed for men. Another cluster in the medial portion of the superior frontal cortex elicited higher activation to the faces by AUDm than NCm, a difference that was more evident than the one observed for women. Together, these findings have added new evidence of AUD-related gender differences in neural responses to facial expressions of emotion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.