Evidence map›Paper›PMID 34106668›Full record

ArticleMedicine2021

Helicobacter pylori reinfection and its risk factors after initial eradication: A protocol for systematic review and meta-analysis.

Renliang Li, Ping Zhang, Ziyi Hu, Ying Yi, Lisha Chen, Hengyi Zhang

Abstract read
In one paragraph

Article in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. BeyondMedicina (Kaunas, Lithuania) · 2025
    Review
  2. Therapeutics and clinical risk management · 2025
    Review
  3. Frontiers in microbiology · 2024
    Article
  4. Treatment ofHeliyon · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Renliang LiJiangxi University of Traditional Chinese Medicine.
Ping ZhangJiangxi University of Traditional Chinese Medicine.
Ziyi HuThe Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province, PR China.
Ying YiJiangxi University of Traditional Chinese Medicine.
Lisha ChenJiangxi University of Traditional Chinese Medicine.
Hengyi ZhangJiangxi University of Traditional Chinese Medicine.

Funding

Research Project for Traditional Chinese Medical Science and Technology of Jiangxi Province No. 2018A010Traditional Chinese Medicine Evidence-based Capacity Building Project 2019XZZX-LG005Training Plan for Young and Middle-aged backbone talents of traditional Chinese Medicine in Jiangxi Province No. 2020-2
6 · The paper itself

Abstract

backgroundHelicobacter pylori (H pylori) infection is a common health problem, which is closely related to peptic ulcers, gastric cancer, and extragastric diseases. Drugs can successfully eradicate it. However, the recurrence of H pylori often occurs after initial eradication. To confirm the global incidence of H pylori reinfection and systematically evaluate its risk factors.

methodsWe will search for the relevant literature through Chinese and English databases, with the retrieval deadline being November 2021. Databases include PubMed, Embase, Web of Science, the Cochrane Library, China National Knowledge Infrastructure, the Chongqing VIP Chinese Science and Technology Periodical Database, Wanfang Database, and China Biomedical Literature Database. Stata14.0 will be used to conduct this systematic review. The preferred reporting items for systematic reviews and meta-analysis protocols statements are followed in this protocol, and the PRISMA statement will be followed in the completed systematic review.

resultsThe results will be published in a peer-reviewed journal.

conclusionsThis systematic review will provide evidence regarding the rate of H pylori reinfection and its risk factors after successful eradication. It can guide the management of patients with H pylori infection.

Indexed as

AdolescentAdultAgedFemaleHelicobacter InfectionsHelicobacter pyloriHumansMaleMeta-Analysis as TopicMiddle AgedReinfectionResearch DesignRisk FactorsSystematic Reviews as TopicYoung Adult

Identifiers

PMID34106668
PMCPMC8133036

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.