Evidence map›Paper›PMID 34106436›Full record

SynthesisSleep & breathing = Schlaf & Atmung2022

A meta-analysis of the diagnostic value of NoSAS in patients with sleep apnea syndrome.

Huimin Chen, Zhenzhen Zheng, Riken Chen, Yu Zeng, Nanhong Li, Jinru Zhu, Yue Zhong, Haimin Liu, Jianmin Lu, Nuofu Zhang and 1 more

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Chinese Guidelines for the Diagnosis and Surgical Treatment of Adult Obstructive Sleep Apnea (2024).World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
  2. Screening Obstructive Sleep Apnea in Chinese Adults: Optimizing STOP-Bang and NoSAS Cutoff Values.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Brazilian Thoracic Association Consensus on Sleep-disordered Breathing.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Huimin ChenDepartment of Traditional Chinese Medicine, The Second Affiliated Hospital of Guangdong Medical University, Guangzhou, China.
Zhenzhen ZhengDepartment of Respiration, The Second Affiliated Hospital of Guangdong Medical University, Guangzhou, China.
Riken ChenChina State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yu ZengDepartment of Respiration, The Second Affiliated Hospital of Guangdong Medical University, Guangzhou, China.
Nanhong LiInstitute of Nephrology, Affiliated Hospital of Guangdong Medical University, Guangzhou, China.
Jinru ZhuDepartment of Respiration, The Second Affiliated Hospital of Guangdong Medical University, Guangzhou, China.
Yue ZhongChina State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Haimin LiuChina State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Jianmin LuChina State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Nuofu ZhangChina State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. nfzhanggird@163.com.
Cheng HongChina State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. gyfyyhc@126.com.ORCID 0000-0002-0710-8757

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe NoSAS score is a new tool widely used in recent years to screen for obstructive sleep apnea. A number of studies have shown that the NoSAS score is more accurate than previous tools, such as the Berlin, STOP-Bang, and STOP questionnaires. Therefore, this meta-analysis assessed the diagnostic value of the NoSAS score for sleep apnea syndrome in comparison to polysomnography.

methodsTwo researchers searched the PubMed, EMBASE, Cochrane, and Web of Science databases through November 13, 2020. This paper used Endnote9.3 software to manage the literature and RevMan 5.3 and STATA12.0 software to perform the meta-analysis.

resultsA total of 10 studies were included in this meta-analysis, including 14,510 patients. The meta-analysis showed that the pooled sensitivity was 0.798 (95% CI 0.757, 0.833), the pooled specificity was 0.582 (95% CI 0.510, 0.651), the positive likelihood ratio was 1.909 (95% CI 1.652, 2.206), the negative likelihood ratio was 0.347 (95% CI 0.300, 0.403), the diagnostic OR was 5.495 (95% CI 4.348, 6.945), and the area under the SROC curve was 0.77 (95% CI 0.73, 0.80). The NoSAS score has good efficacy in identifying patients likely to have obstructive sleep apnea.

conclusionThe NoSAS score can accurately identify patients likely to have obstructive sleep apnea. Therefore, in the absence of polysomnography, one should use the NoSAS score to evaluate patients with suspected sleep apnea syndrome.

Indexed as

Sleep Apnea, ObstructiveSleep Apnea SyndromesBerlinHumansMass ScreeningPolysomnographySurveys and QuestionnairesDiagnosisMeta-analysisNoSAS scoreSleep apnea syndrome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.