ArticleTropical animal health and production2021
Neopterin, procalcitonin, clinical biochemistry, and hematology in calves with neonatal sepsis.
Article in Tropical animal health and production, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 33 citations in OpenAlex.
- Hormonal, biochemical and hematological changes in neonatal calves with sepsis induced by enteritis.Iranian journal of veterinary research · 2026Article
- Pathogen Detection and Analysis of Non-Infectious Factors in Calf Diarrhea at a Large-Scale Dairy Farm in Wuwei City.Veterinary sciences · 2025Article
- A Longitudinal Observational Study on Lactation-Associated Changes in Procalcitonin, Protein Carbonyl Content, Asymmetric Dimethylarginine, and Symmetric Dimethylarginine in Dairy Cattle.Veterinary sciences · 2025Article
- Association BetweenAnimals : an open access journal from MDPI · 2025Article
- Optimization of Antimicrobial Use for Sepsis in Calves: Bayesian Evaluation of Existing and Novel Sepsis Scores.Animals : an open access journal from MDPI · 2025Article
- Chloride and lactate as prognostic indicators of calf diarrhea from eighty-nine cases.Journal of veterinary science · 2024Article
- Neonatal Sepsis: Aetiology, Pathophysiology, Diagnostic Advances and Management Strategies.Clinical medicine insights. Pediatrics · 2024Review
- Case-Control Study: Endogenous Procalcitonin and Protein Carbonylated Content as a Potential Biomarker of Subclinical Mastitis in Dairy Cows.Veterinary sciences · 2023Article
- Procalcitonin as an Endogenous Biomarker for Mastitis in Cows.Animals : an open access journal from MDPI · 2023Article
- Case report: Fatal neonatal sepsis associated withFrontiers in veterinary science · 2023Article
- Pentraxin-3, endothelin-1, some biochemical parameters and hematology in bovine respiratory disease complex.Iranian journal of veterinary research · 2023Article
- Fitness of calves born fromFrontiers in veterinary science · 2022Article
- Clinical and laboratory predictors for bacteremia in critically ill calves.Journal of veterinary internal medicineArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aims to determine how neopterin, procalcitonin, biochemical and hematological parameters change during treatment of calves with neonatal sepsis. A total of 25 calves divided into two groups. Sepsis group was composed of 15 newborn calves aged 0-10 days which met neonatal sepsis criteria, but did not receive any treatment. Control group included 10 healthy calves aged 0-10 days. Clinical examinations (respiratory rate, rectal temperature, heart rate, capillary refill time, sucking reflex) were performed at certain times before (0th h) and during (12th, 24th, 48th, and 72th h) the treatment. The blood was taken from the jugular vein from the sepsis group before (0th h) and during the treatment (12th, 24th, 48th, and 72nd h) and once from the control group. Procalcitonin pretreatment (0th h) and control group concentrations were found as 178.08 ± 2.4 (pg/mL) and 42.78 ± 1.25 (pg/mL), respectively (p < 0.001). Neopterin pretreatment (0th h) and control group concentrations were determined as 14.44 ± 0.30 (ng/mL) and 3.63 ± 0.29 (ng/mL), respectively (p < 0.001). As a result, neopterin and procalcitonin concentration decreased along with the treatment, confirming the presence of sepsis in calves and suggesting that sepsis could be a prognostic indicator. Therefore, both procalcitonin and neopterin can be prognostic and diagnostic in calves with sepsis.
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