ArticleBrain structure & function2022
Fronto-parietal homotopy in resting-state functional connectivity predicts task-switching performance.
Article in Brain structure & function, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sex differences in brain homotopic co-activations: a meta-analytic study.Brain structure & function · 2022Pooled it
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- Aerobic exercise versus acupuncture as adjuncts to acetylcholinesterase inhibitors in Alzheimer's disease: a systematic review and Bayesian network meta-analysis.American journal of clinical and experimental immunology · 2026Review
- Functional divergence between the two cerebral hemispheres contributes to human fluid intelligence.Communications biology · 2025Article
- Common and unique network basis for externally and internally driven flexibility in cognition: From a developmental perspective.Developmental cognitive neuroscience · 2025Article
- Variations in neuronal cytoskeletal integrity affect directed communication in distributed networks during inhibitory control.Communications biology · 2025Article
- A Functional Magnetic Resonance Imaging Investigation of Hot and Cool Executive Functions in Reward and Competition.Sensors (Basel, Switzerland) · 2025Article
- The Impact of Immediate and Delayed Rewards on Task-Switching Performance.Brain sciences · 2025Article
- Neurophysiological effective network connectivity supports a threshold-dependent management of dynamic working memory gating.iScience · 2024Article
- Reduced homotopic interhemispheric connectivity in psychiatric disorders: evidence for both transdiagnostic and disorder specific features.Psychoradiology · 2022Review
- Can Stimulus Valence Modulate Task-Switching Ability? A Pilot Study on Primary School Children.International journal of environmental research and public health · 2022Article
- The Higher, More Complicated: The Neural Mechanism of Hierarchical Task Switching on Prefrontal Cortex.Brain sciences · 2022Review
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Authors and funding
8 authors.
Funding
Abstract
Homotopic functional connectivity reflects the degree of synchrony in spontaneous activity between homologous voxels in the two hemispheres. Previous studies have associated increased brain homotopy and decreased white matter integrity with performance decrements on different cognitive tasks across the life-span. Here, we correlated functional homotopy, both at the whole-brain level and specifically in fronto-parietal network nodes, with task-switching performance in young adults. Cue-to-target intervals (CTI: 300 vs. 1200 ms) were manipulated on a trial-by-trial basis to modulate cognitive demands and strategic control. We found that mixing costs, a measure of task-set maintenance and monitoring, were significantly correlated to homotopy in different nodes of the fronto-parietal network depending on CTI. In particular, mixing costs for short CTI trials were smaller with lower homotopy in the superior frontal gyrus, whereas mixing costs for long CTI trials were smaller with lower homotopy in the supramarginal gyrus. These results were specific to the fronto-parietal network, as similar voxel-wise analyses within a control language network did not yield significant correlations with behavior. These findings extend previous literature on the relationship between homotopy and cognitive performance to task-switching, and show a dissociable role of homotopy in different fronto-parietal nodes depending on task demands.
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