Evidence map›Paper›PMID 34106300›Full record

ReviewHerz2022

[Current aspects of heart-kidney interactions : Summary of important clinical studies from 2020].

Insa E Emrich, Mert Tokcan, Hussam Al Ghorani, Vedat Schwenger, Felix Mahfoud

Open access · hybridAbstract readReview
In one paragraph

Review in Herz, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Insa E EmrichKlinik für Innere Medizin III, Klinik für Kardiologie, Angiologie und Internistische Intensivmedizin, IMED, Universitätsklinikum des Saarlandes, Homburg, Deutschland. insa.emrich@uks.eu.ORCID http://orcid.org/0000-0002-5048-3659
Mert TokcanKlinik für Innere Medizin III, Klinik für Kardiologie, Angiologie und Internistische Intensivmedizin, IMED, Universitätsklinikum des Saarlandes, Homburg, Deutschland.
Hussam Al GhoraniKlinik für Innere Medizin III, Klinik für Kardiologie, Angiologie und Internistische Intensivmedizin, IMED, Universitätsklinikum des Saarlandes, Homburg, Deutschland.
Vedat SchwengerKlinik für Nieren‑, Hochdruck- und Autoimmunerkrankungen, Transplantationszentrum Stuttgart, Klinikum der Landeshauptstadt Stuttgart gKAöR, Stuttgart, Deutschland.
Felix MahfoudKlinik für Innere Medizin III, Klinik für Kardiologie, Angiologie und Internistische Intensivmedizin, IMED, Universitätsklinikum des Saarlandes, Homburg, Deutschland.
Universitätsklinikum des Saarlandes · DEKlinikum Stuttgart · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with chronic kidney diseases show an increased cardiovascular morbidity and mortality. Last year a number of important studies on heart-kidney interaction were published, which are summarized and discussed in this article. In the DAPA-CKD study and the SCORED study two different sodium-glucose linked transporter 2 (SGLT2) inhibitors (dapagliflozin and sotagliflozin) were found to improve the prognosis of patients with chronic kidney diseases with and without diabetes. The results of the randomized study on the new mineralocorticoid receptor antagonist finerenon (FIDELIO-DKD) also provided a very promising novel treatment approach for patients with diabetic nephropathy. The published data of the ISCHEMIA-CKD study in patients with coronary heart disease and investigations on the influence of transcatheter aortic valve implantation (TAVI) on renal function as well as another study on acute kidney failure after MitraClip® (Abbott, Chicago, IL, USA) implantation provide important indications for future treatment recommendations. The optimal timing of the initiation of kidney replacement therapy in patients with acute kidney damage in intensive care medicine was investigated in two randomized studies, which are correspondingly discussed.

Indexed as

Diabetic NephropathiesRenal Insufficiency, ChronicSodium-Glucose Transporter 2 InhibitorsTranscatheter Aortic Valve ReplacementHumansKidneySodium-Glucose Transporter 2 InhibitorsCardiovascular morbidityChronic renal insufficiencyMineralocorticoid receptor antagonistsRenal replacement therapySGLT2 inhibitors

Identifiers

PMID34106300
PMCPMC8948142
OpenAlexW3170084097

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.