Evidence map›Paper›PMID 34105952›Full record

ArticleACS applied materials & interfaces2021

Formulation of Nanovaccines toward an Extended Immunity against Nicotine.

Yun Hu, Zongmin Zhao, Marion Ehrich, Chenming Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yun HuDepartment of Biological Systems Engineering, Virginia Tech, Blacksburg, Virginia 24061, United States.
Zongmin ZhaoDepartment of Biological Systems Engineering, Virginia Tech, Blacksburg, Virginia 24061, United States.
Marion EhrichDepartment of Biomedical Sciences and Pathobiology, Virginia Tech, Blacksburg, Virginia 24061, United States.ORCID https://orcid.org/0000-0002-5466-4203
Chenming ZhangDepartment of Biological Systems Engineering, Virginia Tech, Blacksburg, Virginia 24061, United States.ORCID https://orcid.org/0000-0002-6770-5334

Funding

Novel nanovaccines against opioid use disordersUG3DA048775 · NIDA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI PRAVETONI, MARCO, ZHANG, CHENMING M · 2019 to 2020
$3.1M
Novel Nanovaccines Against Nicotine AddictionU01DA036850 · NIDA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI ZHANG, CHENMING M · 2014 to 2016
$2.3M
Development of novel vaccines against drug abuse - Proof of concept study for vacR21DA030083 · NIDA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI ZHANG, CHENMING M · 2011 to 2012
$385k
NIDA NIH HHS R21 DA030083NIDA NIH HHS U01 DA036850NIDA NIH HHS UG3 DA048775
6 · The paper itself

Abstract

Nicotine vaccines have been investigated to assist with smoking cessation. Because smoking cessation is a long process, past nicotine vaccines required multiple injections to achieve long-term efficacy. It would be of great significance if extended efficacy can be achieved with fewer injections. Here, we report the assembly of lipid-polylactic acid (PLA) and lipid-poly(lactic-

Indexed as

AnimalsBrainFemaleImmunity, HumoralImmunoglobulin GMiceMice, Inbred BALB CNanoparticlesNicotinePolyestersPolylactic Acid-Polyglycolic Acid CopolymerVaccinesImmunoglobulin GNicotinePolyestersPolylactic Acid-Polyglycolic Acid Copolymerpoly(lactide)Vaccinesextended immunityhumoral responseliposome hybrid nanoparticlenicotine vaccinesmoking cessation

Identifiers

PMID34105952
PMCPMC9201939

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.