Evidence map›Paper›PMID 34105734›Full record

ArticleOncology reports2021

Methylation gene

Saipeng Chen, Longfei Xiao, Huahong Peng, Zhen Wang, Jianbing Xie

Open access · hybridAbstract read
In one paragraph

Article in Oncology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Saipeng Chen *Affiliated Hospital of Putian University, Putian, Fujian 351100, P.R. China.
Longfei Xiao *Affiliated Hospital of Putian University, Putian, Fujian 351100, P.R. China.
Huahong PengTianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin 300211, P.R. China.
Zhen WangTaixing People's Hospital, Taixing, Jiangsu 225400, P.R. China.
Jianbing XieAffiliated Hospital of Putian University, Putian, Fujian 351100, P.R. China.
Putian University · CNSecond Hospital of Tianjin Medical University · CNTaixing People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to explore and verify the potential mechanism of seminoma progression. Data on 132 RNA‑seq and 156 methylation sites from stage II/III and I seminoma specimens were downloaded from The Cancer Genome Atlas database. An initial filter of |fold‑change| >2 and false discovery rate <0.05 were used to identify differentially expressed genes (DEGs) which were associated with differential methylation site genes; these genes were considered potential candidates for further investigation by survival analysis. Potassium voltage‑gated channel subfamily C member 1 (

Indexed as

DNA MethylationAdultApoptosisCell ProliferationGene Knockout TechniquesHumansImmunohistochemistryMaleNeoplasm InvasivenessNeoplasm MetastasisReverse Transcriptase Polymerase Chain ReactionRNA, MessengerRNA, Small InterferingSeminomaShaw Potassium ChannelsSurvival RateKCNC1 protein, humanRNA, MessengerRNA, Small InterferingShaw Potassium Channelsdot blotK+ channelsKCNC1methylationseminoma

Identifiers

PMID34105734
PMCPMC8020201
OpenAlexW3138838905

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.