Evidence map›Paper›PMID 34105630›Full record

ArticleRevista da Sociedade Brasileira de Medicina Tropical2021

Laboratory diagnosis of human T-lymphotropic virus in Brazil: assays, flowcharts, challenges, and perspectives.

Adele Caterino-de-Araujo, Edel Figueiredo Barbosa-Stancioli, José Boullosa Alonso Neto, Mayra Gonçalves Aragón, Bernardo Galvão-Castro, Ricardo Ishak, Carolina Rosadas

Abstract read
In one paragraph

Article in Revista da Sociedade Brasileira de Medicina Tropical, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adele Caterino-de-AraujoInstituto Adolfo Lutz, Centro de Imunologia, Laboratório de Pesquisa em HTLV, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0003-0155-6580
Edel Figueiredo Barbosa-StancioliUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Laboratório de Virologia Básica e Aplicada, Belo Horizonte, MG, Brasil.ORCID http://orcid.org/0000-0001-6584-4333
José Boullosa Alonso NetoMinistério da Saúde, Secretaria de Vigilância em Saúde, Departamento de Doenças de Condições Crônicas e Infecções Sexualmente Transmissíveis, Brasília, DF, Brasil.ORCID http://orcid.org/0000-0001-5057-2531
Mayra Gonçalves AragónUniversidade Federal do Espírito Santo, Programa de Pós-Graduação em Doenças Infecciosas, Vitória, ES, Brasil.ORCID http://orcid.org/0000-0001-6631-1790
Bernardo Galvão-CastroEscola Bahiana de Medicina e Saúde Pública, Centro Integrativo e Muldisciplinar de Atendimento ao Portador de HTLV, Salvador, BA, Brasil.ORCID http://orcid.org/0000-0002-0644-6471
Ricardo IshakUniversidade Federal do Pará, Instituto de Ciências Biológicas, Laboratório de Virologia, Belém, PA, Brasil.ORCID http://orcid.org/0000-0002-4741-6201
Carolina RosadasImperial College Healthcare NHS Trust, St. Mary's Hospital, National Centre for Human Retrovirology, London, United Kingdom.ORCID http://orcid.org/0000-0002-3922-5667

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe present a data analysis and review of recent studies regarding the laboratory diagnosis of human T-lymphotropic virus 1 and 2 (HTLV-1/2) infections in Brazil.

methodsTarget populations, available diagnostic serological assays (screening and complementary tests), molecular assays (in-house), causes of false-positive and false-negative results, and flowcharts were analyzed.

resultsA table presents the target populations, two diagnostic flowcharts (depending on laboratory infrastructure and study population), and recent research that may improve how HTLV-1/2 is diagnosed in Brazil.

conclusionsOur results support the implementation of public policies to reduce HTLV-1/2 transmission and its associated diseases.

Indexed as

HTLV-II InfectionsHTLV-I InfectionsHuman T-lymphotropic virus 1BrazilClinical Laboratory TechniquesHumansHuman T-lymphotropic virus 2Software Design

Identifiers

PMID34105630
PMCPMC8186893

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.