ArticleRevista da Sociedade Brasileira de Medicina Tropical2021
Temporal changes in the clinical-epidemiological profile of patients with Chagas disease at a referral center in Brazil.
Article in Revista da Sociedade Brasileira de Medicina Tropical, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- SBC Guideline on the Diagnosis and Treatment of Patients with Cardiomyopathy of Chagas Disease - 2023.Arquivos brasileiros de cardiologia · 2023Guideline
- Observational
- Identification of seropositive cases of Chagas disease in pregnant women in a non-endemic risk area of the state of Mexico: The importance of screening prenatal.Parasite epidemiology and control · 2025Article
- Utility of Magnetic Bead-Based Automated DNA Extraction to Improve Chagas Disease Molecular Diagnosis.International journal of molecular sciences · 2025Article
- Association between transmission modes and chronic Chagas disease clinical forms.Revista da Sociedade Brasileira de Medicina Tropical · 2025Article
- Food insecurity is associated with decreased quality of life in patients with chronic Chagas disease.PloS one · 2025Article
- Impact of COVID-19 In-hospital Mortality in Chagas Disease Patients.Frontiers in medicine · 2022Article
- The association of exercise test variables with long-term mortality in patients with chronic Chagas disease.Frontiers in medicine · 2022Article
- Epidemiological-clinical profile and mortality in patients coinfected with Trypanosoma cruzi/HIV: experience from a Brazilian reference center.Revista da Sociedade Brasileira de Medicina Tropical · 2022Observational
- Cohort profile update: the main and new findings from the SaMi-Trop Chagas cohort.Revista do Instituto de Medicina Tropical de Sao Paulo · 2021Article
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15 authors.
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Abstract
introductionWe aimed to describe the sociodemographic, epidemiological, and clinical characteristics of patients with chronic Chagas disease (CD) at an infectious disease referral center. Changes in patient profiles over time were also evaluated.
methodsThis retrospective study included patients with CD from November 1986-December 2019. All patients underwent an evaluation protocol that included sociodemographic profile; epidemiological history; anamnesis; and physical, cardiologic, and digestive examinations. Trend differences for each 5-year period from 1986 to 2019 were tested using a nonparametric trend test for continuous and generalized linear models with binomial distribution for categorical variables.
resultsA total of 2,168 patients (52.2% women) were included, with a mean age of 47.8 years old. White patients with low levels of education predominated. The reported transmission mode was vectorial in 90.2% of cases. The majority came from areas with a high prevalence (52.2%) and morbidity (67.8%) of CD. The most common clinical presentation was the indeterminate form (44.9%). The number of patients referred gradually decreased and the age at admission increased during the study period, as did the patients' levels of education.
conclusionsThe clinical profile of CD is characterized by a predominance of the indeterminate form of the disease. Regarding the patients who were followed up at the referral center, there was a progressive increase in the mean age and a concomitant decrease in the number of new patients. This reflects the successful control of vector and transfusion transmission in Brazil as well as the aging population of patients with CD.
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