Evidence map›Paper›PMID 34105391›Full record

ArticleCell transplantation

Long-Term Outcome of Sciatic Nerve Regeneration Using Bio3D Conduit Fabricated from Human Fibroblasts in a Rat Sciatic Nerve Model.

Maki Ando, Ryosuke Ikeguchi, Tomoki Aoyama, Mai Tanaka, Takashi Noguchi, Yudai Miyazaki, Shizuka Akieda, Koichi Nakayama, Shuichi Matsuda

Open access · goldAbstract read
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Maki AndoDepartment of Orthopaedic Surgery, 12918Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ryosuke IkeguchiDepartment of Orthopaedic Surgery, 12918Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0003-4525-7849
Tomoki AoyamaDepartment of Orthopaedic Surgery, 12918Kyoto University Graduate School of Medicine, Kyoto, Japan.
Mai TanakaDepartment of Orthopaedic Surgery, 12918Kyoto University Graduate School of Medicine, Kyoto, Japan.
Takashi NoguchiDepartment of Orthopaedic Surgery, 12918Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yudai MiyazakiDepartment of Orthopaedic Surgery, 12918Kyoto University Graduate School of Medicine, Kyoto, Japan.
Shizuka AkiedaDepartment of Orthopaedic Surgery, 12918Kyoto University Graduate School of Medicine, Kyoto, Japan.
Koichi NakayamaDepartment of Orthopaedic Surgery, 12918Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0002-7324-8862
Shuichi MatsudaDepartment of Orthopaedic Surgery, 12918Kyoto University Graduate School of Medicine, Kyoto, Japan.
Saga University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previously, we developed a Bio3D conduit fabricated from human fibroblasts and reported a significantly better outcome compared with artificial nerve conduit in the treatment of rat sciatic nerve defect. The purpose of this study is to investigate the long-term safety and nerve regeneration of Bio3D conduit compared with treatments using artificial nerve conduit and autologous nerve transplantation.We used 15 immunodeficient rats and randomly divided them into three groups treated with Bio3D (

Indexed as

AnimalsDisease Models, AnimalFibroblastsHumansMaleNerve RegenerationRatsSciatic NerveTreatment Outcomebio 3D printernerve conduitnerve regenerationperipheral nerve

Identifiers

PMID34105391
PMCPMC8193652
OpenAlexW3168782523

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.