Evidence map›Paper›PMID 34105309›Full record

ReviewCancer reports (Hoboken, N.J.)2022

Neoadjuvant lenvatinib for inoperable thyroid cancer: A case report and literature review.

Khalid Alshehri, Yousuf Alqurashi, Mazin Merdad, Shaza Samargandy, Razan Daghistani, Hani Marzouki

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Cancer reports (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Association between tracheo-oesophageal fistula and anti-angiogenic therapy in locally advanced/metastatic tumours. A narrative review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026
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  2. Article
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  6. Landmark Studies in Differentiated Thyroid Cancer.Annals of surgical oncology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Khalid AlshehriDepartment of Otorhinolaryngology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.ORCID 0000-0002-6530-1977
Yousuf AlqurashiDepartment of Otorhinolaryngology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Mazin MerdadDepartment of Otorhinolaryngology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Shaza SamargandyEndocrine Unite, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Razan DaghistaniDepartment of Radiology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Hani MarzoukiDepartment of Otorhinolaryngology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
King Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoorly differentiated thyroid cancer (PDTC) is now classified as a separate thyroid tumor entity. It has male predominance and poor prognosis compared to differentiated TC. CASE: We report a case of a patient with PDTC who was previously deemed inoperable. A trial of neoadjuvant lenvatinib therapy was given to the patient after that the tumor become operable and the surgery went successfully.

conclusionsLenvatinib is a feasible option in patients with inoperable TC and can stabilize the lesion size or even reduce it, leading to a more favorable surgical outcome.

Indexed as

FemaleHumansMiddle AgedNeoadjuvant TherapyPhenylurea CompoundsProtein Kinase InhibitorsQuinolinesThyroidectomyThyroid NeoplasmslenvatinibPhenylurea CompoundsProtein Kinase InhibitorsQuinolineslenvatinibneoadjuvantthyroid cancertyrosine kinase inhibitors

Identifiers

PMID34105309
PMCPMC8842697
OpenAlexW3165960430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.