Evidence map›Paper›PMID 34105279›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

Targeted RNA N

Xuena Chen, Qingquan Zhao, Yu-Li Zhao, Guo-Shi Chai, Weisheng Cheng, Zhiju Zhao, Jia Wang, Guan-Zheng Luo, Nan Cao

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 37 citations in OpenAlex.

  1. Programmable ZBTB7A RNA NMolecular cancer · 2026
    Article
  2. Review
  3. The Role of NMedComm · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. H3K27ac Is Essential for Human Naive Pluripotency Modulated by m6A-Driven EP300 Expression.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  8. Article
  9. Article
  10. Exploring the methyl-verse: Dynamic interplay of epigenome and m6A epitranscriptome.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  11. ALKBH5 in development: decoding the multifaceted roles of mFrontiers in molecular biosciences · 2025
    Review
  12. Precision Transcriptome Editing.ACS synthetic biology · 2024
    Review
  13. The regulatory role of mGenes & diseases · 2024
    Review
  14. Programmable RNA NPlant biotechnology journal · 2024
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. CRISPR-based mFrontiers in cell and developmental biology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xuena ChenThe Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Guangdong, 510080, P.R. China.
Qingquan ZhaoThe Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Guangdong, 510080, P.R. China.
Yu-Li ZhaoMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, P.R. China.
Guo-Shi ChaiMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, P.R. China.
Weisheng ChengThe Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Guangdong, 510080, P.R. China.
Zhiju ZhaoThe Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Guangdong, 510080, P.R. China.
Jia WangThe Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Guangdong, 510080, P.R. China.
Guan-Zheng LuoMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, P.R. China.
Nan CaoThe Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Guangdong, 510080, P.R. China.ORCID 0000-0002-1660-4728
Sun Yat-sen University · CN

Funding

Guangdong Innovative and Entrepreneurial Research Team Program 2016ZT06S029National Key R&D Program of China 2018YFA0109100National Key R&D Program of China 2018YFA0109600National Key R&D Program of China 2018YFA050830National Key R&D Program of China 2019YFA0111500National Key R&D Program of China 2019YFA0802203National Natural Science Foundation of China 31771508National Natural Science Foundation of China 31922015National Natural Science Foundation of China 81700233National Natural Science Foundation of China 91753129National Natural Science Foundation of China 92057113Natural Science Foundation of Guangdong Province 2018B030306044
6 · The paper itself

Abstract

Deficiency of the N

Indexed as

AdenosineAlkB Homolog 5, RNA DemethylaseCaspasesCatalytic DomainCell DifferentiationCell LineageCell ProliferationDemethylationEmbryonic Stem CellsHumansMethylationMethyltransferasesPluripotent Stem CellsRNA, MessengerRNA StabilitySOXB1 Transcription FactorsAdenosineALKBH5 protein, humanAlkB Homolog 5, RNA Demethylasecaspase 13CaspasesMethyltransferasesN-methyladenosineRNA, MessengerSOX2 protein, humanSOXB1 Transcription FactorsALKBH5CRISPRdifferentiationm6A RNA modificationpluripotent stem cells

Identifiers

PMID34105279
PMCPMC8188216
OpenAlexW3139213780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.