Evidence map›Paper›PMID 34104975›Full record

ArticleClinical neuroradiology2022

The "Shiny and Thick High Heel Sign" : A novel radiologic sign for detecting intracranial dural arteriovenous fistulas with time-of-flight magnetic resonance angiography.

Hannes Schacht, Inke Regina König, Johannes Hensler, Peter Schramm, Jan Küchler, Claudia Ditz, Alexander Neumann

Open access · hybridAbstract read
In one paragraph

Article in Clinical neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hannes SchachtDepartment of Neuroradiology, University Medical Center Schleswig-Holstein, Lübeck University, Lübeck, Germany. hannes.schacht@uksh.de.ORCID http://orcid.org/0000-0001-5130-9145
Inke Regina KönigInstitute of Medical Biometry and Statistics, University of Lübeck, Lübeck, Germany.ORCID http://orcid.org/0000-0003-0504-6465
Johannes HenslerDepartment of Radiology and Neuroradiology, University Medical Center Schleswig-Holstein, Kiel University, Kiel, Germany.ORCID http://orcid.org/0000-0002-6594-5334
Peter SchrammDepartment of Neuroradiology, University Medical Center Schleswig-Holstein, Lübeck University, Lübeck, Germany.ORCID http://orcid.org/0000-0002-3245-7692
Jan KüchlerDepartment of Neurosurgery, Lübeck University, Lübeck, Germany.ORCID http://orcid.org/0000-0002-2587-3129
Claudia DitzDepartment of Neurosurgery, Lübeck University, Lübeck, Germany.ORCID http://orcid.org/0000-0002-2925-8537
Alexander NeumannDepartment of Neuroradiology, University Medical Center Schleswig-Holstein, Lübeck University, Lübeck, Germany.ORCID http://orcid.org/0000-0002-5651-3900
University of Lübeck · DEChristian-Albrechts-Universität zu Kiel · DEUniversitäres Kinderwunschzentrum Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTogether with the foramen ovale, the middle meningeal artery (MMA) looks like a high heel shoe print on axial time-of-flight magnetic resonance angiography (TOF-MRA) images, with the MMA resembling the heel. Cranial dural arteriovenous fistulas (DAVF) are often fed by the MMA, which can lead to an increase of signal intensity and diameter of this vessel, resulting in a more "shiny" and "thick" high heel print appearance than on the contralateral side. We describe this finding as a novel radiologic sign and provide cut-off values for the ratios of MMA signal intensities and diameters for predicting the presence of a DAVF.

methodsA total of 84 TOF-MRA examinations of 44 patients with DAVFs (40 with unilateral MMA feeders, 4 with bilateral feeders) and of 40 patients without DAVFs were included. Diameters and signal intensities of both MMAs were measured by two raters and evaluated using receiver operating characteristic analysis.

resultsThe diameters of feeding and non-feeding MMAs differed significantly, as did the ratios of signal intensities and of diameters of DAVF and control patients (P < 0.0001). Cut-off values were 1.25 for average signal intensity ratio (shiny high heel sign) and 1.21 for diameter ratio (thick high heel sign). The combination of the "shiny" and the "thick" high heel sign resulted in the highest sensitivity (92.5%) and positive predictive value (95%).

conclusionThe described sign seems promising for the detection of DAVFs with noncontrast-enhanced MRI. The TOF-MRA source images should be reviewed with special attention to the MMA.

Indexed as

Central Nervous System Vascular MalformationsMagnetic Resonance AngiographyHeelHumansMagnetic Resonance ImagingMeningeal ArteriesCentral nervous system vascular disordersMiddle meningeal arteryNeurovascular imagingPulsatile tinnitusRadiologic sign

Identifiers

PMID34104975
PMCPMC9187571
OpenAlexW3168485563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.