Evidence map›Paper›PMID 34104915›Full record

ArticleTurkish archives of pediatrics2021

Cerebral sinovenous thrombosis in children: A single-center experience.

İpek Dokurel Çetin, Cenk Eraslan, Erdem Şimşek, Seda Kanmaz, Hepsen Mine Serin, Deniz Yılmaz Karapınar, Sanem Keskin Yılmaz, Gül Aktan, Hasan Tekgül, Sarenur Gökben

Open access · diamondAbstract read
In one paragraph

Article in Turkish archives of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

İpek Dokurel ÇetinDepartment of Child Health and Diseases, Department of Child Neurology, Ege University School of Medicine, İzmir, Turkey.ORCID 0000-0002-1820-8980
Cenk EraslanDepartment of Radiology, Ege University School of Medicine, İzmir, Turkey.ORCID https://orcid.org/0000-0002-5762-6149
Erdem ŞimşekDepartment of Child Health and Diseases, Department of Child Neurology, Ege University School of Medicine, İzmir, Turkey.ORCID https://orcid.org/0000-0002-4413-8779
Seda KanmazDepartment of Child Health and Diseases, Department of Child Neurology, Ege University School of Medicine, İzmir, Turkey.ORCID 0000-0002-8738-1242
Hepsen Mine SerinDepartment of Child Health and Diseases, Department of Child Neurology, Ege University School of Medicine, İzmir, Turkey.ORCID https://orcid.org/0000-0002-6296-1048
Deniz Yılmaz KarapınarDepartment of Child Health and Diseases, Department of Pediatric Hematology and Oncology, Ege University Faculty of Medicine, İzmir, Turkey.
Sanem Keskin YılmazDepartment of Child Health and Diseases, Department of Child Neurology, Ege University School of Medicine, İzmir, Turkey.ORCID 0000-0002-8719-0665
Gül AktanDepartment of Child Health and Diseases, Department of Child Neurology, Ege University School of Medicine, İzmir, Turkey.ORCID 0000-0002-5367-2236
Hasan TekgülDepartment of Child Health and Diseases, Department of Child Neurology, Ege University School of Medicine, İzmir, Turkey.ORCID 0000-0002-9972-0651
Sarenur GökbenDepartment of Child Health and Diseases, Department of Child Neurology, Ege University School of Medicine, İzmir, Turkey.ORCID 0000-0001-7896-5716
Ege University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe study aimed to evaluate the patients with a diagnosis of cerebral sinovenous thrombosis in terms of clinical findings, etiology and underlying risk factors, imaging findings, treatment, and prognosis in the long term. MATERIALS AND

methodsMedical records of 19 patients whose ages ranged between 0 days and 17 years with clinical and radiological cerebral sinovenous thrombosis in Ege University Department of Child Neurology were retrospectively evaluated.

resultsNine of nineteen cases were female (47.3%). The median age was 84 months (0-201 months). The most common complaint at the presentation was headache (n=12) and the most common physical examination finding was papilledema (n=11). In etiology, otitis/mastoiditis in three cases, iron deficiency anemia in three cases, sinusitis in two cases, catheter use in four cases, Behçet's disease in three cases were determined. The most common observed genetic factors causing thrombosis was methylenetetrahydrofolate reductase mutation. The transverse sinus (68.4%) is the sinus where thrombosis is most frequently observed. As a result of an average follow-up of 12 months (2-72 months), hemiparesis (n=3/19, 15.7%) and epilepsy (n=5/19, 26.3%) were recorded as sequelae findings, and no mortality was observed.

conclusionIn cases presenting with headache, evaluation of papilledema on funduscopic examination should not be skipped. Neurological imaging should be performed in the change of consciousness of poor feeding infants and children with infections in the head and neck area or underlying chronic diseases. When cerebral sinovenous thrombosis is detected, anticoagulant therapy should be started immediately.

Indexed as

Cerebral sinovenous thrombosisneuroimagingpediatric stroketreatment

Identifiers

PMID34104915
PMCPMC8152651
OpenAlexW3172413975

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.