Evidence map›Paper›PMID 34104907›Full record

ReviewTurkish archives of pediatrics2021

Breast milk stem cells: Are they magic bullets in neonatology?

Sinem Gülcan Kersin, Eren Özek

Open access · diamondAbstract readReview
In one paragraph

Review in Turkish archives of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Breast Milk Stem Cells in the Treatment of Neonatal Diseases.Current stem cell research & therapy · 2025
    Review
  4. Feasibility of intranasal human milk as stem cell therapy in preterm infants with intraventricular hemorrhage.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sinem Gülcan KersinDivision of Neonatology, Department of Pediatrics, Marmara University School of Medicine, İstanbul, Turkey.ORCID 0000-0003-3634-3243
Eren ÖzekDivision of Neonatology, Department of Pediatrics, Marmara University School of Medicine, İstanbul, Turkey.ORCID 0000-0002-6419-5068
Marmara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Each mammal produces milk specific to its newborn that meets all nutritional needs. Breast milk is not only a secretory product but is also a complex liquid containing several components that provide enteral nutrition. The stage of lactation, the fullness of the breast, the feeding of the baby, and the health of the mother during the breastfeeding period cause differences in the composition of breast milk. Although the positive effects of breast milk on the physical and intellectual development of a child in the short and long term have been known for centuries, its mechanism has not been elucidated. Stem cells are defined as the cells that possess specific markers and have not undergone differentiation. Under suitable conditions and stimuli, they can differentiate into desired cells. The detection of stem cells, whose exact origin is not known, in breast milk and their demonstration in the baby's body have prompted the necessity of exploring the possible role of stem cells in the treatment of diseases. In this review, breast milk-derived stem cells and their possible role in neonatology are discussed.

Indexed as

Bronchopulmonary dysplasiahuman breast milkhypoxic-ischemic encephalopathyintraventricular hemorrhagenecrotizing enterocolitisstem cell

Identifiers

PMID34104907
PMCPMC8152646
OpenAlexW3166127339

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.