Evidence map›Paper›PMID 34104843›Full record

ArticleJournal of the Endocrine Society2021

Sociodemographic Disparities in the Treatment of Hypothyroidism: NHANES 2007-2012.

Matthew D Ettleson, Antonio C Bianco, Mengqi Zhu, Neda Laiteerapong

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Social Determinants of Health and Disparities in Thyroid Care.The Journal of clinical endocrinology and metabolism · 2024
    Article
  4. Suboptimal Thyroid Hormone Replacement Is Associated With Worse Hospital Outcomes.The Journal of clinical endocrinology and metabolism · 2022
    Article
  5. Disparities in Thyroid Care.Endocrinology and metabolism clinics of North America · 2022
    Review
  6. Article
  7. Optimal Thyroid Hormone Replacement.Endocrine reviews · 2022
    Article
  8. Clearing Up the Fog: Insights Into Brain Fog Experienced by Patients With Hypothyroidism.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matthew D EttlesonSection of Endocrinology, Diabetes and Metabolism, Universtity of Chicago, Chicago, IL 60637, USA.ORCID https://orcid.org/0000-0003-0328-1752
Antonio C BiancoSection of Endocrinology, Diabetes and Metabolism, Universtity of Chicago, Chicago, IL 60637, USA.ORCID https://orcid.org/0000-0001-7737-6813
Mengqi ZhuSection of General Internal Medicine, University of Chicago, Chicago, IL 60637, USA.
Neda LaiteerapongSection of General Internal Medicine, University of Chicago, Chicago, IL 60637, USA.ORCID https://orcid.org/0000-0003-0124-4325
University of Chicago · US

Funding

Pilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI Raghavendra G Mirmira · 2013 to 2026
$20.9M
Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI Ronald T. Ackermann, MARSHALL H CHIN · 2011 to 2026
$10.0M
INTERGRATED CLINICAL AND BASIC ENDOCRINOLOGY RESEARCHT32DK007011 · NIDDK · UNIVERSITY OF CHICAGO · PI Raghavendra G Mirmira · 1986 to 2026
$5.8M
NIDDK NIH HHS P30 DK020595NIDDK NIH HHS P30 DK092949NIDDK NIH HHS T32 DK007011
6 · The paper itself

Abstract

purposeBoth undertreatment and overtreatment of hypothyroidism with thyroid hormone are associated with adverse clinical outcomes. Disparities in the treatment of hypothyroidism may lead to a higher risk of adverse outcomes for certain sociodemographic groups. Our objectives were to identify sociodemographic disparities between those with treated and untreated hypothyroidism, and between those who were adequately and inadequately treated.

methodsThis is a cross-sectional study of a representative sample of US adults aged 20 years and older with hypothyroidism (n = 698). The main measures were age, gender, race/ethnicity, education, income, and health care access differences among those with treated and untreated hypothyroidism.

resultsOf those with hypothyroidism, women were more likely than men to be taking thyroid hormone (odds ratio [OR] 2.66 [95% confidence interval (CI) 1.42-4.99]), as were older participants (45-69 years old vs 20-44 years old: OR 7.25 [95% CI 4.15-12.67]; 70 years of age and older: OR 11.00 [95% CI 5.30-22.79]). Health care access was strongly associated with thyroid hormone use (OR 14.32, 95% CI 3.63-56.58). Hispanic race/ethnicity was associated with inadequate treatment compared with non-Hispanic whites (OR 2.42, 95% CI: 1.14-5.14). MAIN

conclusionsMale gender, younger age, and lack of health care access were associated with untreated hypothyroidism, and Hispanic race was associated with inadequate treatment of hypothyroidism. Clinicians should be aware of these sociodemographic disparities in the hypothyroid population and consider strategies to improve treatment of hypothyroidism in men, younger adults, Hispanics, and those without routine health care access.

Indexed as

disparitieshypothyroidismsociodemographicthyroid hormone

Identifiers

PMID34104843
PMCPMC8156978
OpenAlexW3136042714

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.