Evidence map›Paper›PMID 34104821›Full record

ReviewJournal of clinical and translational research2021

Advances in multimodal treatment for stage IIIA-N2 non-small cell lung cancer.

Sara Montemuiño Muñiz, Soraya Marcos Sánchez, Julia Calzas Rodríguez, Beatriz Losada Vila, Esther Llorente Herrero, María Dolores Hisado Díaz, Victoria Valeri-Busto González, Begoña Taboada Valladares, Blanca Vaquero Barrón, Francisco José Marcos Jimenez and 4 more

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical and translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Treatment of non-small cell lung cancer: advances following the introduction of PET-CT and IMRT/VMAT.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Sara Montemuiño MuñizDepartment of Radiation Oncology, Hospital Universitario de Fuenlabrada, Camino del Molino, 2, 28942, Fuenlabrada, Madrid, Sara Montemuiño, Spain.
Soraya Marcos SánchezDepartment of Radiation Oncology, Hospital Universitario de Fuenlabrada, Camino del Molino, 2, 28942, Fuenlabrada, Madrid, Sara Montemuiño, Spain.
Julia Calzas RodríguezDepartment of Medical Oncology, Hospital Universitario de Fuenlabrada, Camino del Molino, 2, 28942, Fuenlabrada, Madrid, Spain.
Beatriz Losada VilaDepartment of Medical Oncology, Hospital Universitario de Fuenlabrada, Camino del Molino, 2, 28942, Fuenlabrada, Madrid, Spain.
Esther Llorente HerreroDepartment of Nuclear Medicine, Hospital Universitario de Fuenlabrada, Camino del Molino, 2, 28942, Fuenlabrada, Madrid, Spain.
María Dolores Hisado DíazDepartment of Pulmonology, Hospital Universitario de Fuenlabrada, Camino del Molino, 2, 28942, Fuenlabrada, Madrid, Spain.
Victoria Valeri-Busto GonzálezDepartment of Pulmonology, Hospital Universitario de Fuenlabrada, Camino del Molino, 2, 28942, Fuenlabrada, Madrid, Spain.
Begoña Taboada ValladaresDepartment of Radiation Oncology, Complexo Hospitalario Universitario Santiago de Compostela, Choupana s/n, bloque d, Santiago de Compostela, A Coruña, Spain.
Blanca Vaquero BarrónDepartment of Radiation Oncology, Hospital Universitario de La Princesa, C/Diego de León, 62, 28006, Madrid, Spain.
Francisco José Marcos JimenezDepartment of Radiation Oncology, Hospital Universitario de Cáceres, Avda, Universidad 75, 10004, Cáceres, Extremadura, Spain.
Sergio Amor AlonsoDepartment of Thoracic Surgery, Hospital Universitario Quirónsalud Madrid, C/Diego de Velázquez, 1, 28223, Pozuelo de Alarcón, Madrid, Spain.
Javier MoradiellosDepartment of Thoracic Surgery, Hospital Universitario Quirónsalud Madrid, C/Diego de Velázquez, 1, 28223, Pozuelo de Alarcón, Madrid, Spain.
Núria Rodríguez de DiosDepartment of Radiation Oncology, Hospital del Mar, Passeig Marítim, 25-29, 08003 Barcelona, Spain.
Felipe CouñagoDepartment of Radiation Oncology, Hospital Universitario Quirónsalud Madrid, C/Diego de Velázquez, 1, 28223, Pozuelo de Alarcón, Madrid, Spain.
Hospital del Mar Research Institute · ESUniversidad Europea de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimIn Stage IIIA-N2 non-small cell lung cancer (NSCLC), the accuracy of combined positron-emission tomography/computed tomography imaging (PET-CT), together with mediastinal staging techniques, has led to a wide range of challenging clinical scenarios in terms of therapeutic management. Concurrent chemoradiotherapy followed by consolidation immunotherapy remains the standard of care. In patients with potentially-resectable disease, surgery plays an important role in multimodal therapy. The introduction of targeted therapies and immune-checkpoint inhibitors has revolutionized multimodal treatment. In the present article, we review current treatment options and future trends in stage IIIA-N2 NSCLC. RELEVANCE FOR PATIENTS: This article provides insight into the current status of multimodal treatment for NSCLC to support decision-making in routine clinical practice.

Indexed as

chemoradiationimmunotherapyneoadjuvant treatmentnon-small cell lung cancerstage IIIAsurgery

Identifiers

PMID34104821
PMCPMC8177852
OpenAlexW3170816561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.