ReviewResearch and reports in urology2021
Current Perspectives on the Diagnosis and Management of Primary Urethral Cancer: A Systematic Review.
Review in Research and reports in urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Urethrectomy with glans reconstruction and meatoplasty for rare high-grade urothelial carcinoma in distal urethra.Urology case reports · 2026Article
- Article
- Female Urethral Adenocarcinoma Posing a Diagnostic Challenge.Clinical case reports · 2025Article
- Organ-preserving surgery for male distal primary urethral carcinoma: A case report from a tertiary hospital in Ethiopia.International journal of surgery case reports · 2025Article
- Primary urethral carcinoma in female: An extremely rare case series at a single tertiary referral hospital and literature review.International journal of surgery case reports · 2024Article
- Research Progress of PD 1/PD L1 Inhibitors in the Treatment of Urological Tumors.Current cancer drug targets · 2024Review
- Morphologic spectrum of the epithelial tumors of the male and female urethra.Virchows Archiv : an international journal of pathology · 2023Review
- Exploring the role of natural bioactive molecules in genitourinary cancers: how far has research progressed?Natural products and bioprospecting · 2023Review
- A case report: Female primary urethral carcinoma presenting as vulval mass.International journal of surgery case reports · 2023Article
- A multimodality review of male urethral imaging: pearls and pitfalls with an update on urethral stricture treatment.The British journal of radiology · 2022Review
- Primary urothelial carcinoma of the male anterior urethra; A case report.Annals of medicine and surgery (2012) · 2022Article
- [70/m presenting with macrohematuria, palpable penile mass, and obstructive voiding symptoms : Preparation for the medical specialist examination: part 21].Der Urologe. Ausg. A · 2022Article
- Advanced Female Primary Urethral Carcinoma with Nodal Extension Managed with Exclusive Use of Chemoradiotherapy: Report of a Case and Review of the Relevant Current Literature.Case reports in oncologyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary urethral cancer (PUC) is a rare but highly aggressive malignancy that causes malignant urethral obstruction. We conducted a literature review using PubMed to identify original research studies that assessed the diagnosis and management of primary urethral cancer. PUC affects men more than women, is more common in African Americans than Caucasians, and is associated with history of chronic inflammation and irritation of the urinary tract. Patients suspected of PUC should undergo a complete work-up including cystoscopy, magnetic resonance imaging, and biopsy. In men and women, surgical monotherapy ranging from organ-sparing to more radical reconstructive procedures has adequate survival rates for early stage PUC and has been shown to be similarly as effective as radiation monotherapy, while multimodal therapy has become the standard of treatment for advanced stage PUC. Salvage surgery or radiation therapy has been linked with increased survival rates. Nodal involvement at the time of diagnosis is a negative prognosticator and should be treated with multimodal therapy. Further prospective studies with greater sample sizes and standardized clinical trials would allow for greater consistency in evaluating the different treatment modalities for PUC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.