ReviewCureus2021
Hyperuricemia and Cardiovascular Risk.
Review in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Association between metabolic syndrome and uric acid: a systematic review and meta-analysis.Scientific reports · 2022Pooled it
- Article
- Uric Acid Extremes and Lipid Dysregulation: Evidence from a Large Population-Based Study.Metabolites · 2026Article
- Prevalence of hyperuricemia among patients with non-communicable diseases in Ethiopia: a systematic review and meta-analysis.Cardiovascular diabetology. Endocrinology reports · 2026Review
- The relationship between cardiometabolic index and hyperuricemia and gout in Korean adults: the 8th Korean National Health and Nutrition Examination Survey (2019-2021).Clinical rheumatology · 2026Article
- Serum Uric Acid Levels and Risk of Atrial Fibrillation in Heart Failure Patients.Current cardiology reviews · 2026Article
- The Cognitive Changes Among Patients over 65 Years of Age in a Rural Area-The Preliminary Report of Protective and Predisposing Factors.Neurology international · 2025Article
- Treatment of gouty lumbar spinal stenosis: a case report and bioinformatics analysis.BMC musculoskeletal disorders · 2025Article
- Network Pharmacology Combined with Experimental Validation to Investigate the Mechanism of the Anti-Hyperuricemia Action ofNutrients · 2024Article
- Does Serum Uric Acid Mediate Relation between Healthy Lifestyle and Components of Metabolic Syndrome?Nutrients · 2024Article
- Non-Interventional Weight Changes Are Associated with Alterations in Serum Uric Acid Levels.Journal of clinical medicine · 2024Article
- Mushroom consumption and cardiometabolic health outcomes in the general population: a systematic review.Nutrition research and practice · 2024Review
- Diabetes and gout: another role for SGLT2 inhibitors?Therapeutic advances in endocrinology and metabolism · 2024Article
- Higher Atherogenic Index of Plasma Is Associated with Hyperuricemia: A National Longitudinal Study.International journal of endocrinology · 2024Article
- Prevalence of hyperuricaemia among adults from Ningxia Hui Autonomous Region, China: a cross-sectional study.BMJ open · 2023Article
- Utility of coronary artery calcium in refining 10-year ASCVD risk prediction using a Thai CV risk score.Frontiers in cardiovascular medicine · 2023Article
- The association of metabolic risk factors with ischemic heart disease and heart failure in Saudi Arabia - A cross sectional study.Journal of family medicine and primary care · 2022Article
- A retrospective observational study of serum uric acid and in-hospital mortality in acute type A aortic dissection.Scientific reports · 2022Observational
- Acute oral toxicity assessment and anti-hyperuricemic activity ofSaudi journal of biological sciences · 2022Article
- The Impact of an Elevated Uric Acid Level on the Prevalence of Coronary Artery Disease in Pancreas Transplant Candidates with Type 1 Diabetes: A Cross Sectional Study.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As the prevalence of hyperuricemia (elevated uric acid levels in the blood) increases, the relationship between serum uric acid levels and cardiovascular risk has garnered increased interest. Several studies have highlighted that elevated uric acid levels are likely tied to increased cardiovascular disease risk. Specifically, the presence of hyperuricemia is well-established to contribute to the onset of gout (an inflammatory condition characterized by painful/swollen joints). Several studies have shown that the risk of developing gout is strongly associated with the degree of hyperuricemia. In this review, we will provide insight into the association between gout and cardiovascular disease risk. It is also important to gain insight into the pathophysiology of gout to understand the contributions to cardiovascular disease risk as well as improve diagnosis and target treatment more effectively. An interdisciplinary approach for gout management and areas for further investigation will be discussed in this review.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.