Evidence map›Paper›PMID 34104454›Full record

ArticleCanadian journal of kidney health and disease2021

In Search of a Better Outcome: Opting Into the Live Donor Paired Kidney Exchange Program.

Amanda J Vinson, Bryce A Kiberd, Karthik K Tennankore

Abstract read
In one paragraph

Article in Canadian journal of kidney health and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amanda J VinsonDepartment of Medicine, Dalhousie University, Halifax, NS, Canada.ORCID https://orcid.org/0000-0002-9345-5252
Bryce A KiberdDepartment of Medicine, Dalhousie University, Halifax, NS, Canada.
Karthik K TennankoreDepartment of Medicine, Dalhousie University, Halifax, NS, Canada.ORCID https://orcid.org/0000-0002-7919-6709

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLive donor (LD) kidney transplantation is the best option for patients with end-stage kidney disease (ESKD). However, this may not be the best option if a patient's donor is older and considerably smaller in weight. Patient (A) with a less than ideal donor (Donor A) might enter into a live donor paired exchange (LDPE) program with the hopes of swapping for a better-quality organ. A second patient (B) who is in the LDPE may or may not benefit from this exchange with Donor A.

methodsThis medical decision analysis examines the conditions that favor Patient A entering into the LDPE compared to directly accepting a kidney from their intended donor, as well as the circumstances where Patient B also benefits by accepting a lower-quality organ.

resultsUnder select circumstances, a paired exchange could benefit both Patients A and B. For example, a 30-year-old Patient A with a lower-quality donor might gain

conclusionThis study shows there are ways to increase live donor utilization and effectiveness that require further research and potentially changes to the LDPE process.

Indexed as

allocationkidney paired exchangekidney transplantationliving kidney donationmedical decision analysis

Identifiers

PMID34104454
PMCPMC8161848

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.