Evidence map›Paper›PMID 34104284›Full record

ArticleRadiology case reports2021

Acute necrotic hemorrhagic leukoencephalitis related to COVID-19: a report of 2 cases.

Alwaleed Alqahtani, Aeed Alaklabi, Stefan Kristjansson, Hanan Alharthi, Suhayb Aldhilan, Hamid Alam

Open access · goldAbstract readCase Reports
In one paragraph

Article in Radiology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Acute hemorrhagic leukoencephalitis: a case report and systematic review of factors associated with severe disability and death.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Alwaleed AlqahtaniRadiology Department, Security Forces Hospital, Riyadh, Saudi Arabia.
Aeed AlaklabiRadiology Department, Security Forces Hospital, Riyadh, Saudi Arabia.
Stefan KristjanssonRadiology Department, King Faisal Specialist Hospital, Riyadh, Saudi Arabia.
Hanan AlharthiRadiology Department, King Faisal Specialist Hospital, Riyadh, Saudi Arabia.
Suhayb AldhilanRadiology Department, Prince Sultan Military Medical Hospital, Riyadh, Saudi Arabia.
Hamid AlamRadiology Department, Brookhaven Memorial Hospital Medical Center in Patchogue, New York, NY, USA.
King Faisal Specialist Hospital & Research Centre · SASecurity Forces Hospital · SALong Island Community Hospital · USRiyadh Armed Forces Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute necrotic hemorrhagic leukoencephalitis (ANHLE) is a subform of acute disseminating leukoencephalitis which is a post viral or vaccination uncommon disease with poor prognosis. Radiological findings include multiple or diffuse lesions involving the white matter and sparing the cortex with or without rim enhancement. In addition to areas of hemorrhages with possible involvement of basal ganglia and thalami. We describe the imaging findings for 2 cases of ANHLE; a 59-years-old male and a 47-years-old female. Both of them were tested positive of SARS-COVID2 with presentation of consciousness loss and respiratory failure. CT and MRI brain show global white matter changes associated with acute hemorrhagic necrosis, although uncommon, are compatible with postviral acute necrotic hemorrhagic leukoencephalitis with end point of death for the first patient and coma for the second patient.

Indexed as

Acute hemorrhagic necrosisBrainCoronavirusCOVID-19CT, computed tomographyDM, diabetes mellitusDNR, do not resuscitationEEG, electroencephalogramESRD, end stage renal diseaseGCS, Glasgow Coma ScoreHTN, hypertensionICU, intensive care unitMRI, magnetic resonance imagingNeuroimagingSARS-COVID2SARS-COVID2, COVID-19VAP, ventilator associated pneumoniaWhite matter disease

Identifiers

PMID34104284
PMCPMC8173541
OpenAlexW3167726173

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.