Evidence map›Paper›PMID 34104272›Full record

ReviewCanadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC

Community pharmacist prescribing of antimicrobials: A systematic review from an antimicrobial stewardship perspective.

Julie Hui-Chih Wu, Fatima Khalid, Bradley J Langford, Nathan P Beahm, Mark McIntyre, Kevin L Schwartz, Gary Garber, Valerie Leung

Open access · hybridAbstract readReview
In one paragraph

Review in Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 3 countries.

Julie Hui-Chih WuPublic Health Ontario, Ontario.
Fatima KhalidScarborough Health Network, Scarborough.
Bradley J LangfordPublic Health Ontario, Ontario.
Nathan P Beahmthe Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta.ORCID https://orcid.org/0000-0002-5095-8570
Mark McIntyrethe Sinai Health-University Health Network Antimicrobial Stewardship Program, University Health Network, Toronto.
Kevin L SchwartzPublic Health Ontario, Ontario.
Gary GarberPublic Health Ontario, Ontario.
Valerie LeungPublic Health Ontario, Ontario.ORCID https://orcid.org/0000-0002-6780-5378
3M (United States) · USHotel Dieu Shaver Health and Rehabilitation Centre · CAPublic Health Ontario · CAScarborough General Hospital · GBToronto East General Hospital · CAUniversity Health Network · CAUniversity of Alberta · CAUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPharmacist prescribing authority is expanding, while antimicrobial resistance is an increasing global concern. We sought to synthesize the evidence for antimicrobial prescribing by community pharmacists to identify opportunities to advance antimicrobial stewardship in this setting.

methodsWe conducted a systematic review to characterize the existing literature on community pharmacist prescribing of systemic antimicrobials. We searched MEDLINE, EMBASE and International Pharmaceutical Abstracts for English-language articles published between 1999 and June 20, 2019, as well as hand-searched reference lists of included articles and incorporated expert suggestions.

resultsOf 3793 articles identified, 14 met inclusion criteria. Pharmacists are most often prescribing for uncomplicated urinary tract infection (UTI), acute pharyngitis and cold sores using independent and supplementary prescribing models. This was associated with high rates of clinical improvement (4 studies), low rates of retreatment and adverse effects (3 studies) and decreased health care utilization (7 studies). Patients were highly satisfied (8 studies) and accessed care sooner or more easily (7 studies). Seven studies incorporated antimicrobial stewardship into study design, and there was overlap between study outcomes and those relevant to outpatient antimicrobial stewardship. Pharmacist intervention reduced unnecessary prescribing for acute pharyngitis (2 studies) and increased the appropriateness of prescribing for UTI (3 studies).

conclusionThere is growing evidence to support the role of community pharmacists in antimicrobial prescribing. Future research should explore additional opportunities for pharmacist antimicrobial prescribing and ways to further integrate advanced antimicrobial stewardship strategies in the community setting.

Identifiers

PMID34104272
PMCPMC8165883
OpenAlexW3139927610

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.