Evidence map›Paper›PMID 34104156›Full record

ArticlePakistan journal of medical sciences

Impact of acne on quality of life in young Pakistani adults and its relationship with severity: A multicenter study.

Shaheen Naveed, Sadia Masood, Atiya Rahman, Safia Awan, Saadia Tabassum

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07392047 (Comparison Of The Efficacy Of 2% Metronidazole Gel Versus 1% Clindamycin Gel In The Treatment Of Moderate Acne Vulgaris), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07392047 phase4not yet recruitingnot on this map

Comparison Of The Efficacy Of 2% Metronidazole Gel Versus 1% Clindamycin Gel In The Treatment Of Moderate Acne Vulgaris

TypeinterventionalSponsorJinnah Postgraduate Medical CentreRan2026 to 2026Enrolled60ConditionsAcne VulgarisArmsMetronidazole Topical Gel 2%, Clindamycin Topical Gel 1%
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Shaheen NaveedDr. Shaheen Naveed, MBBS, FCPS. Assistant Professor of Dermatology, Liquate National Hospital, Karachi, Pakistan.
Sadia MasoodDr. Sadia Masood, MBBS, FCPS, MHPE. Assistant Professor of Dermatology, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Atiya RahmanDr. Atiya Rahman, MBBS, FCPS. Associate Professor of Dermatology, Combined Military Hospital Lahore, Pakistan.
Safia AwanMs. Safia Awan, MSC. Senior Instructor, Research, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Saadia TabassumDr. Saadia Tabassum, MBBS, FCPS. Assistant Professor of Dermatology, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Aga Khan University Hospital · PKCombined Military Hospital · PKLiaquat National Hospital · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe current study aimed to determine the effect of acne vulgaris on quality of life of young adults and to assess the correlation between acne severity and impairment of quality of life (QOLI).

methodsIn this multi-center cross-sectional study, 163 young adults with acne vulgaris were assessed for severity and quality of life impairment between December 2016 and May 2017 at three tertiary care hospitals. Cardiff Acne Disability Index (CADI) was used to assess the quality of life while the severity of acne measured by Global Acne Grading System (GAGS). Data were collected on standardized forms, with CADI, GAGS scores, and sociodemographic data and analyzed using SPSS version 9. The quantitative variables were presented as means, median and qualitative variables expressed as frequency and percentages. P-value ≤0.05 was considered as statistically significant.

resultsOut of 163 patients enrolled in this study, the mean age was 21.6 ± 4.9 years and 124 were females and 39 males. In mild QOLI, 56 (87.5%) cases were affected with mild, 11 (13.4%) with moderate and 1 (1.5%) case had severe acne. While, in moderate QOLI, 8(12.5%) cases were of mild, 60 (73.2%) were moderate and 6 (35.3%) cases affected with severe acne. The severe impairment of QOL noted in 11 (13.4%) moderate and 10 (58.8%) severe acne cases. The relationship between sex was statistically significant, (P<0.001). The result showed significant correlation between severity of acne vulgaris and the quality of life impairment of these patients (P<0.001).

conclusionThis study showed significant correlation between acne vulgaris and quality of life impairment. Cardiff acne disability index has proven to be a reliable tool to assess the quality of life. It is recommended to be used routinely in dermatology clinics to provide tailored treatment to individuals because mild disease may be disproportionately distressing for patients.

Indexed as

Acne VulgarisImpairmentQuality of lifeSeverity

Identifiers

PMID34104156
PMCPMC8155408
OpenAlexW3134301278

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.