Evidence map›Paper›PMID 34103957›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2021

Blood Levels of Glycated Hemoglobin, D-Dimer, and Fibrinogen in Diabetic Retinopathy.

Heng Zhao, Li-Dan Zhang, Li-Fang Liu, Chun-Qing Li, Wei-Li Song, Yong-Yang Pang, Yun-Liang Zhang, Dan Li

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Analysis of Risk Factors for Revitrectomy in Eyes with Diabetic Vitreous Hemorrhage.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Article
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Heng Zhao *Endocrinology Laboratory, The First Central Hospital of Baoding, Baoding, Hebei Province, 071000, People's Republic of China.
Li-Dan Zhang *Department of Nuclear Medicine, The First Central Hospital of Baoding, Baoding, Hebei Province, 071000, People's Republic of China.
Li-Fang LiuEndocrinology Laboratory, The First Central Hospital of Baoding, Baoding, Hebei Province, 071000, People's Republic of China.
Chun-Qing LiOutpatient Department, The First Central Hospital of Baoding, Baoding, Hebei Province, 071000, People's Republic of China.
Wei-Li SongOutpatient Department, The First Central Hospital of Baoding, Baoding, Hebei Province, 071000, People's Republic of China.
Yong-Yang PangEndocrinology Laboratory, The First Central Hospital of Baoding, Baoding, Hebei Province, 071000, People's Republic of China.
Yun-Liang ZhangEndocrinology Laboratory, The First Central Hospital of Baoding, Baoding, Hebei Province, 071000, People's Republic of China.
Dan LiDepartment of Ophthalmology, Affiliated Hospital of Hebei University, Baoding, Hebei Province, 071000, People's Republic of China.
Baoding People's Hospital · CNAffiliated Hospital of Hebei University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to describe the levels of glycated hemoglobin (HbA1c), D-dimer (D-D), and fibrinogen (FIB) in different types of diabetic retinopathy (DR).

methodsA total of 61 patients with diabetes, who were treated in our department between November 2017 and May 2019, were selected. According to their non-mydriatic fundus photography and fundus angiography results, patients were divided into three groups, ie, the non-DR (NDR) group (n=23), the non-proliferative DR (NPDR) group (n=17), and the proliferative DR (PDR) group (n=21). A control group of 20 people who had tested negative for diabetes was also included. The levels of HbA1c, D-D, and FIB were measured and compared, respectively.

resultsThe mean values of HbA1c were 6.8% (5.2%, 7.7%), 7.4% (5.8%, 9.0%), and 8.5% (6.3%, 9.7%) in the NDR, NPDR, and PDR groups, respectively. The control group values were 4.9% (4.1%, 5.8%). These results indicated a significant statistical difference between groups. The mean values of D-D were 0.39 ± 0.21 mg/L, 1.06 ± 0.54 mg/L, and 1.39 ± 0.59 mg/L in the NDR, NPDR, and PDR groups, respectively. The control group result was 0.36 ± 0.17 mg/L. The values of the NPDR and PDR groups were significantly higher than those of the NDR and control groups, and the value of the PDR group was significantly higher than that of the NPDR group, indicating a significant difference between the groups (

conclusionBlood levels of HbA1c, D-D, and FIB in the PDR group were significantly higher than in the NPDR group.

Indexed as

D-DD-dimerdiabetic retinopathyDRFIBfibrinogenglycated hemoglobinHbA1cmicroangiopathy

Identifiers

PMID34103957
PMCPMC8180300
OpenAlexW3166807953

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.