ArticleJournal of anaesthesiology, clinical pharmacology
Effect of oral gabapentin premedication on hemodynamic parameters and postoperative pain in patients of laparoscopic cholecystectomy: A randomized double-blind controlled study.
Article in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 6 citations in OpenAlex.
- Ondansetron versus gabapentin in preventing postoperative nausea and vomiting after laparoscopic sleeve gastrectomy: a randomized study.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsCarbon dioxide (CO MATERIAL AND
methodsRandomly selected 60 American Society of Anesthesiologists (ASA) class I patients scheduled for laparoscopic cholecystectomy were premedicated with either gabapentin 1200 mg (Group GB) or placebo (Group PL) 2 h prior to induction of anesthesia. Anesthesia was induced with fentanyl, propofol, and vecuronium; and maintained with oxygen (33%), nitrous oxide (66%), and isoflurane (1%) with controlled ventilation. Hemodynamic parameters were recorded at various time intervals intraoperatively and during pneumoperitoneum every 10 min till 50 min. Postoperatively visual analog score (VAS) for pain, incidence of PONV, and sedation score were recorded for 6 h. The collected data were analyzed statistically by using repeated measures analysis of variance (ANOVA), Student's
resultsChanges in mean BP, systolic BP, and diastolic BP from prepneumoperitoneum values were significantly less in group GB during pneumoperitoneum (
conclusionOral gabapentin premedication may be used to control hemodynamic parameters during pneumoperitoneum in patients undergoing laparoscopic cholecystectomy.
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