Evidence map›Paper›PMID 34103629›Full record

Trial reportScientific reports2021

Probing penile hemodynamics by using photoplethysmography as objective indicators for male erection quality and sexual function.

Yuan-Hung Pong, Yi-Kai Chang, Ching-En Hsu, Po-Cheng Chen, Yu-Chuan Lu, Vincent F S Tsai, Hong-Chiang Chang, Men-Tzung Lo, Chen Lin

Open access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yuan-Hung Pong *Department of Biomedical Sciences and Engineering, National Central University, Taoyuan, 320, Taiwan.
Yi-Kai Chang *Department of Urology, National Taiwan University Hospital, Taipei, 100, Taiwan.
Ching-En HsuDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, 320, Taiwan.
Po-Cheng ChenDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, 320, Taiwan.
Yu-Chuan LuDepartment of Urology, National Taiwan University Hospital, Taipei, 100, Taiwan.
Vincent F S TsaiDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, 320, Taiwan.
Hong-Chiang ChangDepartment of Urology, National Taiwan University Hospital, Taipei, 100, Taiwan.
Men-Tzung LoDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, 320, Taiwan.
Chen LinDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, 320, Taiwan. clin@ncu.edu.tw.
National Central University · TWNational Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erectile dysfunction (ED) is mostly due to the lack of blood flow into the penis. In the past 20 years, near-infrared spectroscopy (NIRS) was used in measuring the concentrations and temporal dynamics of different hemoglobin types. However, the dynamics of the light absorption (photoplethysmography; PPG) have not been applied to survey penile hemodynamics and erection quality. This paper compared the use of photoplethysmography (PPG) to study vascular ED with standard penile Doppler ultrasonography. Men diagnosed with vascular ED for at least 6 months and nominated for penile ultrasonography were included. PPG signals were collected during the ultrasound examination. All beat-to-beat PPG waveforms were aligned with the peak and averaged to one representative template waveform for feature analysis, including amplitude differences (APD) index, reflection time index (RTI), augmentation index (AI), and perfusion index (PI). An inverse correlation was found between end-erection amplitude and both erection hardness score (EHS) and resistive index (RI). APD index and EHS as well as the international index of erectile function-5 (IIEF) and RI were positively correlated. RTI and AI were inversely correlated to IIEF and RI. PI was positively correlated to RI. PPG may therefore be useful as a noninvasive, convenient, technique for sexual function evaluation.

Indexed as

PhotoplethysmographyAgedHemodynamicsHumansMaleMiddle AgedPenile ErectionPenis

Identifiers

PMID34103629
PMCPMC8187730
OpenAlexW3172419855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.