ArticleProceedings of the National Academy of Sciences of the United States of America2021
Early life stress is associated with earlier emergence of permanent molars.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06701240 (Examining Effects of a Strengths-based Community-grounded Intervention for Parents and Their Young Children), which is not on this map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Examining Effects of a Strengths-based Community-grounded Intervention for Parents and Their Young Children
Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Primary tooth emergence in young children is associated with a stress biomarker.Journal of developmental origins of health and disease · 2026Article
- Rural-Urban and Demographic Inequalities in Dental Pathology and Diagnostic Patterns in Romanian Emergency Care: A Retrospective Tertiary Clinical Cohort Study.Healthcare (Basel, Switzerland) · 2026Article
- MRI-based dental maturity in newborns reflects prenatal exposures and predicts timing of primary tooth eruption.bioRxiv : the preprint server for biology · 2026Article
- Effects of intergenerational parent-child separation on early eruption of permanent molar and telomere length: a cross-sectional study among Chinese children aged 3-6 years.BMC oral health · 2026Article
- Impact of conflict-induced stress on dental and skeletal development in children and adolescents.The Angle orthodontist · 2026Article
- Longitudinal associations between early-life adversity and accelerated molar eruption: the dimensional and cumulative approach.BMC oral health · 2025Article
- Prenatal maternal salivary hormones and timing of tooth eruption in early childhood: a prospective birth cohort study.Frontiers in oral health · 2025Article
- Effects of Early Life Scarcity-Adversity on Maturational Milestones in Male and Female Rats.Developmental psychobiology · 2024Article
- Infant and early childhood physical health assessments in the HEALthy Brain and Child Development (HBCD) Study.Developmental cognitive neuroscience · 2024Article
- Can social adversity alter the epigenome, trigger oral disease, and affect future generations?Irish journal of medical science · 2024Review
- The central role of the individual in the history of brains.Neuroscience and biobehavioral reviews · 2024Review
- Helpless infants are learning a foundation model.Trends in cognitive sciences · 2024Review
- The promise and pitfalls of a strength-based approach to child poverty and neurocognitive development: Implications for policy.Developmental cognitive neuroscience · 2024Article
- Developmental Correlates of Accelerated Molar Eruption in Early Childhood.Biological psychiatry global open science · 2023Article
- Individual differences in T1w/T2w ratio development during childhood.Developmental cognitive neuroscience · 2023Article
- Intrinsic activity development unfolds along a sensorimotor-association cortical axis in youth.Nature neuroscience · 2023Article
- Social Epigenomics: Conceptualizations and Considerations for Oral Health.Journal of dental research · 2022Review
- Accelerated pubertal development as a mechanism linking trauma exposure with depression and anxiety in adolescence.Current opinion in psychology · 2022Review
- Exploring neural correlates of behavioral and academic resilience among children in poverty.Developmental cognitive neuroscience · 2022Article
- Protocol for a Case Control Study to Evaluate Oral Health as a Biomarker of Child Exposure to Adverse Psychosocial Experiences.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Exposure to adversity can accelerate biological aging. However, existing biomarkers of early aging are either costly and difficult to collect, like epigenetic signatures, or cannot be detected until late childhood, like pubertal onset. We evaluated the hypothesis that early adversity is associated with earlier molar eruption, an easily assessed measure that has been used to track the length of childhood across primates. In a preregistered analysis (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.